Structure DeltaA1-A4 insulin

Summary for 2W44

DescriptorINSULIN, RESORCINOL, ZINC ION, ... (6 entities in total)
Functional Keywordsinsulin, hormone
Biological sourceHOMO SAPIENS
Cellular locationSecreted  A6XGL2 A6XGL2
Total number of polymer chains6
Total molecular weight16385.47
Thorsoee, K.S.,Schlein, M.,Brandt, J.,Schluckebier, G.,Naver, H. (deposition date: 2008-11-21, release date: 2009-12-22, Last modification date: 2018-01-17)
Primary citation
Thorsoe, K.S.,Schlein, M.,Steensgaard, D.B.,Brandt, J.,Schluckebier, G.,Naver, H.
Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform.
Biochemistry, 49:6234-, 2010
PubMed: 20568733 (PDB entries with the same primary citation)
DOI: 10.1021/BI1000118
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.284609.8%4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution