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3VH8
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BU of 3vh8 by Molmil
KIR3DL1 in complex with HLA-B*5701
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2011-08-24
Release date:2011-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B
Nature, 479, 2011
5B39
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KIR3DL1*015 in complex with HLA-B*57:01
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2016-02-12
Release date:2016-03-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition
J.Exp.Med., 213, 2016
2QTJ
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BU of 2qtj by Molmil
Solution structure of human dimeric immunoglobulin A
Descriptor: Ig alpha-1 chain C region, Kappa light chain IgA1
Authors:Bonner, A, Furtado, P.B, Almogren, A, Kerr, M.A, Perkins, S.J.
Deposit date:2007-08-02
Release date:2008-01-22
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy
J.Immunol., 180, 2008
7T0R
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BU of 7t0r by Molmil
Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Adnectin 6940_B01, Ibalizumab Heavy Chain, ...
Authors:Williams, S.P, Concha, N.O, Wensel, D.L, Hong, X.
Deposit date:2021-11-30
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J.Mol.Biol., 434, 2021
7T0O
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BU of 7t0o by Molmil
cryoEM reconstruction of the HIV gp140 in complex with the extracellular domains of CD4 and the adnectin domain of Combinectin. The gp140 and CD4 coordinates from entry 6EDU were rigid body fitted to the EM map along withe the crystal structure of CD4+adnectin
Descriptor: Adnectin, BG505 SOSIP.664 gp140, T-cell surface glycoprotein CD4
Authors:Concha, N.O, William, S.P, Wenzel, D.L.
Deposit date:2021-11-30
Release date:2022-01-12
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J.Mol.Biol., 434, 2021
6EDU
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BU of 6edu by Molmil
B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21c Fab VH domain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2018-08-11
Release date:2018-10-17
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
5B38
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BU of 5b38 by Molmil
KIR3DL1*005 in complex with HLA-B*57:01
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2016-02-12
Release date:2016-03-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition
J.Exp.Med., 213, 2016
6EFY
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BU of 6efy by Molmil
Crystal Structure of DIP-Alpha Ig1-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein alpha, isoform A, ...
Authors:Cosmanescu, F, Shapiro, L.
Deposit date:2018-08-17
Release date:2018-11-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins.
Neuron, 100, 2018
1CDJ
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BU of 1cdj by Molmil
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4
Descriptor: T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H, Myszka, D, Tendian, S.W, Brouillette, C.G, Sweet, R.W, Chaiken, I.M, Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
4YH6
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BU of 4yh6 by Molmil
Crystal structure of IL1RAPL1 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-27
Release date:2015-05-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
1CDH
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BU of 1cdh by Molmil
STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES
Descriptor: T CELL SURFACE GLYCOPROTEIN CD4
Authors:Ryu, S.E, Truneh, A, Sweet, R.W, Hendrickson, W.A.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices.
Structure, 2, 1994
1CDI
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BU of 1cdi by Molmil
STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES
Descriptor: T CELL SURFACE GLYCOPROTEIN CD4
Authors:Ryu, S.E, Truneh, A, Sweet, R.W, Hendrickson, W.A.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices.
Structure, 2, 1994
1CDY
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BU of 1cdy by Molmil
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER
Descriptor: T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H, Myszka, D, Tendian, S.W, Brouillette, C.G, Sweet, R.W, Chaiken, I.M, Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CDU
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BU of 1cdu by Molmil
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH PHE 43 REPLACED BY VAL
Descriptor: T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H, Myszka, D, Tendian, S.W, Brouillette, C.G, Sweet, R.W, Chaiken, I.M, Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
4YBH
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BU of 4ybh by Molmil
Crystal structure of the human RAGE ectodomain (VC1C2 fragment) in complex with human S100A6
Descriptor: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ...
Authors:Yatime, L, Andersen, G.R.
Deposit date:2015-02-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.
Structure, 24, 2016
5CAY
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BU of 5cay by Molmil
Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120 core from ST strain of HIV-2, ...
Authors:Davenport, Y.W, Bjorkman, P.J.
Deposit date:2015-06-30
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an HIV-2 gp120 in Complex with CD4.
J.Virol., 90, 2015
3WUW
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BU of 3wuw by Molmil
KIR3DL1 in complex with HLA-B*57:01.I80T
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2014-05-06
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity
J.Immunol., 192, 2014
7TTZ
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BU of 7ttz by Molmil
Heterodimeric IgA Fc in complex with Staphylococcus aureus protein SSL7
Descriptor: 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Boulanger, M.J, Verstraete, M, Heinkel, F, Escobar, E, Dixit, S, Von Kreudenstein, T.S.
Deposit date:2022-02-02
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics.
Mabs, 14, 2022
7TXD
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BU of 7txd by Molmil
Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ...
Authors:Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2022-02-08
Release date:2023-04-12
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
2X1X
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BU of 2x1x by Molmil
CRYSTAL STRUCTURE OF VEGF-C IN COMPLEX WITH DOMAINS 2 AND 3 OF VEGFR2 IN A TETRAGONAL CRYSTAL FORM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, ...
Authors:Leppanen, V.-M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K.
Deposit date:2010-01-08
Release date:2010-02-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2.
Proc.Natl.Acad.Sci.USA, 107, 2010
4BFI
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BU of 4bfi by Molmil
Structure of the complex of the extracellular portions of mouse CD200R and mouse CD200
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1, ...
Authors:Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N.
Deposit date:2013-03-19
Release date:2013-05-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution
Structure, 21, 2013
2X1W
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BU of 2x1w by Molmil
Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CESIUM ION, ...
Authors:Leppanen, V.M, Prota, A.E, Jeltsch, M, Anisimov, A, Kalkkinen, N, Strandin, T, Lankinen, H, Goldman, A, Ballmer-Hofer, K, Alitalo, K.
Deposit date:2010-01-08
Release date:2010-03-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Determinants of Growth Factor Binding and Specificity by Vegf Receptor 2.
Proc.Natl.Acad.Sci.USA, 107, 2010
1JL4
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BU of 1jl4 by Molmil
CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE
Descriptor: H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ...
Authors:Wang, J.-H, Meijers, R, Reinherz, E.L.
Deposit date:2001-07-15
Release date:2001-09-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
Proc.Natl.Acad.Sci.USA, 98, 2001
1N26
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BU of 1n26 by Molmil
Crystal Structure of the extra-cellular domains of Human Interleukin-6 Receptor alpha chain
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Varghese, J.N, Moritz, R.L, Lou, M.-Z, van Donkelaar, A, Ji, H, Ivancic, N, Branson, K.M, Hall, N.E, Simpson, R.J.
Deposit date:2002-10-22
Release date:2002-12-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the extracellular domains of the human interleukin-6 receptor alpha-chain.
Proc.Natl.Acad.Sci.USA, 99, 2002
1OLZ
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BU of 1olz by Molmil
The ligand-binding face of the semaphorins revealed by the high resolution crystal structure of SEMA4D
Descriptor: SEMAPHORIN 4D
Authors:Love, C.A, Harlos, K, Mavaddat, N, Davis, S.J, Stuart, D.I, Jones, E.Y, Esnouf, R.M.
Deposit date:2003-08-19
Release date:2003-09-11
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Ligand-Binding Face of the Semaphorins Revealed by the High-Resolution Crystal Structure of Sema4D
Nat.Struct.Biol., 10, 2003

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