2QTJ

Solution structure of human dimeric immunoglobulin A

Summary for 2QTJ

• Entry DOI: 10.2210/pdb2qtj/pdb
• Related: 1iga 2esg
• Descriptor: Kappa light chain IgA1, Ig alpha-1 chain C region (2 entities in total)
• Functional Keywords: x-ray and neutron solution scattering, immunology, antibody, immunoglobulin a1, chromophore, glycoprotein, immunoglobulin c region, immunoglobulin domain, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted : P01876
• Total number of polymer chains: 8
• Total formula weight: 297140.61

Authors

Bonner, A.,Furtado, P.B.,Almogren, A.,Kerr, M.A.,Perkins, S.J. (deposition date: 2007-08-02, release date: 2008-01-22, Last modification date: 2024-02-21)

• Primary citation: Bonner, A.,Furtado, P.B.,Almogren, A.,Kerr, M.A.,Perkins, S.J.; Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy; J.Immunol., 180:1008-1018, 2008; PubMed: 18178841

Experimental method

SOLUTION SCATTERING