2QTJ
Solution structure of human dimeric immunoglobulin A
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR192-HIS198 | |
| A | PHE433-HIS439 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1452 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | GLN1-LEU364 | |
| B | GLN1-LEU364 | |
| C | GLN1-LEU364 | |
| D | GLN1-LEU364 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 72 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN365-LEU383 | |
| B | ASN365-LEU383 | |
| C | ASN365-LEU383 | |
| D | ASN365-LEU383 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 56 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | VAL384-TYR398 | |
| B | VAL384-TYR398 | |
| C | VAL384-TYR398 | |
| D | VAL384-TYR398 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | CARBOHYD: O-linked (GalNAc...) serine => ECO:0000269|PubMed:4373463 |
| Chain | Residue | Details |
| A | GLY105 | |
| D | GLY105 | |
| D | THR119 | |
| D | SER121 | |
| A | THR119 | |
| A | SER121 | |
| B | GLY105 | |
| B | THR119 | |
| B | SER121 | |
| C | GLY105 | |
| C | THR119 | |
| C | SER121 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:20823119, ECO:0000269|PubMed:31959827 |
| Chain | Residue | Details |
| A | LYS106 | |
| D | LYS106 | |
| D | PHE109 | |
| D | LEU117 | |
| A | PHE109 | |
| A | LEU117 | |
| B | LYS106 | |
| B | PHE109 | |
| B | LEU117 | |
| C | LYS106 | |
| C | PHE109 | |
| C | LEU117 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | CARBOHYD: O-linked (GalNAc...) serine => ECO:0000269|PubMed:20823119, ECO:0000269|PubMed:31959827, ECO:0000269|PubMed:4373463 |
| Chain | Residue | Details |
| A | TYR111 | |
| A | GLY113 | |
| B | TYR111 | |
| B | GLY113 | |
| C | TYR111 | |
| C | GLY113 | |
| D | TYR111 | |
| D | GLY113 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:31959827 |
| Chain | Residue | Details |
| A | GLN114 | |
| B | GLN114 | |
| C | GLN114 | |
| D | GLN114 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:22171320 |
| Chain | Residue | Details |
| A | VAL144 | |
| B | VAL144 | |
| C | VAL144 | |
| D | VAL144 |
