4YBH
Crystal structure of the human RAGE ectodomain (VC1C2 fragment) in complex with human S100A6
Summary for 4YBH
Entry DOI | 10.2210/pdb4ybh/pdb |
Related | 4P2Y |
Descriptor | Advanced glycosylation end product-specific receptor, Protein S100-A6, ZINC ION, ... (7 entities in total) |
Functional Keywords | signaling complex, pattern recognition receptor, dimerization, ef-hand calcium binding protein, immunoglobulin domain, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 10: Cell membrane ; Single-pass type I membrane protein : Q15109 Nucleus envelope: P06703 |
Total number of polymer chains | 2 |
Total formula weight | 43894.57 |
Authors | Yatime, L.,Andersen, G.R. (deposition date: 2015-02-18, release date: 2016-03-02, Last modification date: 2024-01-10) |
Primary citation | Yatime, L.,Betzer, C.,Jensen, R.K.,Mortensen, S.,Jensen, P.H.,Andersen, G.R. The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins. Structure, 24:2043-2052, 2016 Cited by PubMed: 27818100DOI: 10.1016/j.str.2016.09.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report