4YBH

Crystal structure of the human RAGE ectodomain (VC1C2 fragment) in complex with human S100A6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Advanced glycosylation end product-specific receptor	polymer	304	32680.3	1	UniProt (Q15109) Pfam (PF08205) Pfam (PF13927) In PDB	Homo sapiens (Human)	Receptor for advanced glycosylation end products
2	B	Protein S100-A6	polymer	92	10321.9	1	UniProt (P06703) Pfam (PF01023) In PDB	Homo sapiens (Human)	Calcyclin,Growth factor-inducible protein 2A9,MLN 4,Prolactin receptor-associated protein,PRA,S100 calcium-binding protein A6
3	A, B	ZINC ION	non-polymer		65.4	7	Chemie (ZN)
4	A, B	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
5	A	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
6	B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
7		water	water		18.0	208	Chemie (HOH)

Sequence modifications

A: 23 - 323 (UniProt: Q15109)

PDB	External Database	Details
Gly 20	-	expression tag
Ala 21	-	expression tag
Met 22	-	expression tag

B: 1 - 90 (UniProt: P06703)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43002.2
Non-Polymers*	Number of molecules	17
	Total formula weight	892.4
All*	Total formula weight	43894.6

*Water molecules are not included.