4YBH
Crystal structure of the human RAGE ectodomain (VC1C2 fragment) in complex with human S100A6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Advanced glycosylation end product-specific receptor | polymer | 304 | 32680.3 | 1 | UniProt (Q15109) Pfam (PF08205) Pfam (PF13927) | Homo sapiens (Human) | Receptor for advanced glycosylation end products |
| 2 | B (B) | Protein S100-A6 | polymer | 92 | 10321.9 | 1 | UniProt (P06703) Pfam (PF01023) | Homo sapiens (Human) | Calcyclin,Growth factor-inducible protein 2A9,MLN 4,Prolactin receptor-associated protein,PRA,S100 calcium-binding protein A6 |
| 3 | C, D, E, F, N... (A, B) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 4 | G, H, I, J, Q (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 5 | K, L, M (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | R, S (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 208 | Chemie (HOH) |
Sequence modifications
A: 23 - 323 (UniProt: Q15109)
B: 1 - 90 (UniProt: P06703)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | - | expression tag |
| Ala 21 | - | expression tag |
| Met 22 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43002.2 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 892.4 | |
| All* | Total formula weight | 43894.6 |
