Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0001726 | cellular_component | ruffle |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005523 | molecular_function | tropomyosin binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005634 | cellular_component | nucleus |
| B | 0005635 | cellular_component | nuclear envelope |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007165 | biological_process | signal transduction |
| B | 0007409 | biological_process | axonogenesis |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| B | 0015075 | molecular_function | monoatomic ion transmembrane transporter activity |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0044548 | molecular_function | S100 protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048146 | biological_process | positive regulation of fibroblast proliferation |
| B | 0048306 | molecular_function | calcium-dependent protein binding |
| B | 0048471 | cellular_component | perinuclear region of cytoplasm |
| B | 0062023 | cellular_component | collagen-containing extracellular matrix |
| B | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | ASP160 |
| A | ASP201 |
| A | CL406 |
| A | CL407 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | ASP128 |
| A | HIS180 |
| A | GLU182 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 403 |
| Chain | Residue |
| A | HOH507 |
| A | HOH550 |
| A | GLU32 |
| A | HIS217 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 404 |
| Chain | Residue |
| A | HIS270 |
| A | CL408 |
| A | HOH544 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | GLU132 |
| A | ARG228 |
| A | ZN412 |
| B | PHE16 |
| B | HIS17 |
| B | HIS27 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 406 |
| Chain | Residue |
| A | ASP160 |
| A | ASP201 |
| A | ZN401 |
| A | CL407 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 407 |
| Chain | Residue |
| A | ASP160 |
| A | ASP201 |
| A | ZN401 |
| A | CL406 |
| A | HOH640 |
| B | HOH206 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 408 |
| Chain | Residue |
| A | HIS270 |
| A | ZN404 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue ACT A 409 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 410 |
| Chain | Residue |
| A | ARG77 |
| A | LEU79 |
| A | VAL302 |
| A | THR304 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 411 |
| Chain | Residue |
| A | THR55 |
| A | ARG57 |
| A | TRP72 |
| A | ASP93 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 412 |
| Chain | Residue |
| A | GLU132 |
| A | CL405 |
| B | HIS17 |
| B | HIS27 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 101 |
| Chain | Residue |
| B | CYS3 |
| B | ARG55 |
| B | ASP59 |
| B | HOH201 |
| B | HOH205 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue ZN B 102 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 103 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 104 |
| Chain | Residue |
| B | SER20 |
| B | GLU23 |
| B | ASP25 |
| B | THR28 |
| B | GLU33 |
| B | HOH207 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 105 |
| Chain | Residue |
| B | ASP61 |
| B | ASN63 |
| B | ASP65 |
| B | GLU67 |
| B | GLU72 |
| B | HOH224 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DRNKDQEVNfqEY |
| Chain | Residue | Details |
| B | ASP61-TYR73 | |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCVATH |
| Chain | Residue | Details |
| A | TYR299-HIS305 | |
| site_id | PS00303 |
| Number of Residues | 22 |
| Details | S100_CABP S-100/ICaBP type calcium binding protein signature. LMedLDrnkDqevNFqEYvtFL |
| Chain | Residue | Details |
| B | LEU56-LEU77 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| B | THR28 | |
| B | GLU33 | |
| Chain | Residue | Details |
| B | ASP61 | |
| B | ASN63 | |
| B | ASP65 | |
| B | GLU67 | |
| B | GLU72 | |
| Chain | Residue | Details |
| B | LYS40 | |
| Chain | Residue | Details |
| B | SER46 | |
| Chain | Residue | Details |
| B | LYS47 | |
