1N26

Crystal Structure of the extra-cellular domains of Human Interleukin-6 Receptor alpha chain

Summary for 1N26

• Entry DOI: 10.2210/pdb1n26/pdb
• Related: 1I1R 1IL6 1N2Q
• Descriptor: IL-6 Receptor alpha chain, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: transmembrane, glycoprotein, immunoglobulin domain, cytokine
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38541.88

Authors

Varghese, J.N.,Moritz, R.L.,Lou, M.-Z.,van Donkelaar, A.,Ji, H.,Ivancic, N.,Branson, K.M.,Hall, N.E.,Simpson, R.J. (deposition date: 2002-10-22, release date: 2002-12-18, Last modification date: 2024-04-03)

• Primary citation: Varghese, J.N.,Moritz, R.L.,Lou, M.-Z.,van Donkelaar, A.,Ji, H.,Ivancic, N.,Branson, K.M.,Hall, N.E.,Simpson, R.J.; Structure of the extracellular domains of the human interleukin-6 receptor alpha-chain.; Proc.Natl.Acad.Sci.USA, 99:15959-15964, 2002; PubMed: 12461182; DOI: 10.1073/pnas.232432399

Experimental method

X-RAY DIFFRACTION (2.4 Å)