1I1R

CRYSTAL STRUCTURE OF A CYTOKINE/RECEPTOR COMPLEX

Summary for 1I1R

• Entry DOI: 10.2210/pdb1i1r/pdb
• Descriptor: INTERLEUKIN-6 RECEPTOR BETA CHAIN, VIRAL IL-6 (3 entities in total)
• Functional Keywords: cytokine-receptor complex, gp130, viral il-6, cytokine
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P40189
• Total number of polymer chains: 2
• Total formula weight: 55521.30

Authors

Chow, D.,He, X.,Snow, A.L.,Rose-John, S.,Garcia, K.C. (deposition date: 2001-02-02, release date: 2001-03-28, Last modification date: 2023-08-09)

• Primary citation: Chow, D.,He, X.,Snow, A.L.,Rose-John, S.,Garcia, K.C.; Structure of an extracellular gp130 cytokine receptor signaling complex.; Science, 291:2150-2150, 2001; PubMed: 11251120; DOI: 10.1126/science.1058308

Experimental method

X-RAY DIFFRACTION (2.4 Å)