1JL4

CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE

Summary for 1JL4

Related1IAK 3CD4 1WIO 1G9M
DescriptorH-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K BETA CHAIN, OVOTRANSFERRIN, ... (4 entities in total)
Functional Keywordsprotein-protein complex, immune system
Biological sourceMus musculus (house mouse)
More
Cellular locationMembrane ; Single-pass type I membrane protein  P01910 P06343
Secreted P02789
Cell membrane ; Single-pass type I membrane protein  P01730
Total number of polymer chains4
Total molecular weight63743.58
Authors
Wang, J.-H.,Meijers, R.,Reinherz, E.L. (deposition date: 2001-07-15, release date: 2001-09-19, Last modification date: 2017-10-04)
Primary citation
Wang, J.H.,Meijers, R.,Xiong, Y.,Liu, J.H.,Sakihama, T.,Zhang, R.,Joachimiak, A.,Reinherz, E.L.
Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
Proc.Natl.Acad.Sci.USA, 98:10799-10804, 2001
PubMed: 11535811 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.191124098
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (4.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers 0.40030 2.0% 9.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169117
PDB entries from 2020-09-23