PDB: 282 件ウェブページステータス検索Chemie searchBIRD

---

8OS5	Crystal structure of the Factor XII heavy chain reveals an interlocking dimer with a FnII to kringle domain interaction 分子名称: Coagulation factor XII-Mie 著者 Li, C, Saleem, M, Kaira, B.G, Brown, A, Wilson, C, Philippou, H, Emsley, J. 登録日 2023-04-18 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood, 136, 2020
8U4L	Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... 著者 Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. 登録日 2023-09-10 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain To Be Published
8U4I	Structure of the HER4/NRG1b Homodimer Extracellular Domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... 著者 Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. 登録日 2023-09-10 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain To Be Published
8CN9	Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII 分子名称: CALCIUM ION, CESIUM ION, Coagulation factor VII, ... 著者 Schluckebier, G, Johansson, E. 登録日 2023-02-22 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders Nat Cardiovasc Res, 2023
8ET0	Crystal Complex of murine Cyclooxygenase-2 with alpaca nanobody F9 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IBUPROFEN, ... 著者 Xu, S, Banerjee, S, Uddin, M.J, Goodman, M.C, Marnett, L.J. 登録日 2022-10-15 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal complex of murine cycloxygenase-2 with alpaca nanobody F9 To Be Published
8EOK	Structure of the C3bB proconvertase in complex with lufaxin and factor Xa 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activated factor Xa heavy chain, Complement C3 beta chain, ... 著者 Andersen, J.F, Lei, H. 登録日 2022-10-03 公開日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
8D1B	CryoEM structure of human orphan GPCR GPR179 in complex with extracellular matrix protein pikachurin 分子名称: Pikachurin, Probable G-protein coupled receptor 179 著者 Patil, D.N, Martemyanov, K.A. 登録日 2022-05-27 公開日 2023-07-26 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179. Sci.Signal., 16, 2023
7YBB	Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with D-4-hydroxy-2-oxoglutarate and factor X-derived peptide (39mer-4Ser) 分子名称: (2~{R})-2-oxidanyl-4-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... 著者 Nakashima, Y, Brewitz, L, Schofield, C.J. 登録日 2022-06-29 公開日 2023-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with D-4-hydroxy-2-oxoglutarate and factor X-derived peptide (39mer-4Ser) To Be Published
7YBC	Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with (S)-4-hydroxy-4-methyl-2-oxoglutarate and factor X-derived peptide (39mer-4Ser) 分子名称: (2~{S})-2-methyl-2-oxidanyl-4-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... 著者 Nakashima, Y, Brewitz, L, Schofield, C.J. 登録日 2022-06-29 公開日 2023-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with (S)-4-hydroxy-4-methyl-2-oxoglutarate and factor X-derived peptide (39mer-4Ser) To Be Published
7YB8	Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with D-2-hydroxyglutarate and factor X-derived peptide (39mer-4Ser) 分子名称: (2R)-2-hydroxypentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... 著者 Nakashima, Y, Brewitz, L, Schofield, C.J. 登録日 2022-06-29 公開日 2023-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with D-2-hydroxyglutarate and factor X-derived peptide (39mer-4Ser) To Be Published
7YB9	Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with L-2-hydroxyglutarate and factor X-derived peptide (39mer-4Ser) 分子名称: (2S)-2-HYDROXYPENTANEDIOIC ACID, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... 著者 Nakashima, Y, Brewitz, L, Schofield, C.J. 登録日 2022-06-29 公開日 2023-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with L-2-hydroxyglutarate and factor X-derived peptide (39mer-4Ser) To Be Published
8S9P	1:1:1 agrin/LRP4/MuSK complex 分子名称: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ... 著者 Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C. 登録日 2023-03-29 公開日 2023-05-17 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8HGS	The EGF-bound EGFR ectodomain homodimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Pro-epidermal growth factor, ... 著者 Zhang, Z, Bai, X. 登録日 2022-11-15 公開日 2023-02-15 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3.81 Å) 主引用文献 Structure and dynamics of the EGFR/HER2 heterodimer. Cell Discov, 9, 2023
8HGO	The EGF-bound EGFR/HER2 ectodomain complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor, ... 著者 Zhang, Z, Bai, X. 登録日 2022-11-15 公開日 2023-02-08 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Structure and dynamics of the EGFR/HER2 heterodimer. Cell Discov, 9, 2023
7QAB	NMR Solution Structure of mussel adhesive protein Pvfp-5b 分子名称: PVFP-5 著者 Morando, M.A, Venturella, F, Pastore, A, Alfano, C. 登録日 2021-11-16 公開日 2022-08-03 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of recombinant Pvfp-5 beta reveals insights into mussel adhesion. Commun Biol, 5, 2022
7TPQ	Cryo-em structure of human prothrombinase on a nanodisc at 5.3 Angstrom resolution 分子名称: Activated factor Xa heavy chain, Coagulation factor Va, Factor X light chain 著者 Di Cera, E, Ruben, E.A. 登録日 2022-01-25 公開日 2022-05-04 最終更新日 2022-06-29 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 Cryo-EM structure of the prothrombin-prothrombinase complex. Blood, 139, 2022
7TPP	Cryo-em structure of human prothrombin:prothrombinase at 4.1 Angstrom resolution 分子名称: Activated factor Xa heavy chain, Coagulation factor Va, Factor X light chain, ... 著者 Di Cera, E, Ruben, E.A. 登録日 2022-01-25 公開日 2022-05-04 最終更新日 2022-06-29 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structure of the prothrombin-prothrombinase complex. Blood, 139, 2022
7OM4	Nanobody EgB4 bound to the full extracellular EGFR-EGF complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor, Epidermal growth factor receptor, ... 著者 Zeronian, M.R, Janssen, B.J.C. 登録日 2021-05-21 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (6.05 Å) 主引用文献 Structural insights into the non-inhibitory mechanism of the anti-EGFR EgB4 nanobody. Bmc Mol Cell Biol, 23, 2022
7SYE	Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF. "tips-separated" conformation 分子名称: Epidermal growth factor, Epidermal growth factor receptor 著者 Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. 登録日 2021-11-24 公開日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor. Elife, 10, 2021
7SZ0	Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-juxtaposed" conformation 分子名称: Epidermal growth factor, Epidermal growth factor receptor 著者 Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. 登録日 2021-11-25 公開日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor. Elife, 10, 2021
7SZ1	Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-separated" conformation 分子名称: Epidermal growth factor, Epidermal growth factor receptor 著者 Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. 登録日 2021-11-25 公開日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor. Elife, 10, 2021
7SYD	Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF "tips-juxtaposed" conformation 分子名称: Epidermal growth factor, Epidermal growth factor receptor 著者 Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J. 登録日 2021-11-24 公開日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor. Elife, 10, 2021
7MN8	Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain bound to Trastuzumab Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... 著者 Diwanji, D, Trenker, R, Verba, K.A, Jura, N. 登録日 2021-04-30 公開日 2021-11-10 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface. Nature, 600, 2021
7ALJ	Structure of Drosophila Notch EGF domains 11-13 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus Notch protein, ... 著者 Suckling, R, Johnson, S, Lea, S.M. 登録日 2020-10-06 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling. Embo Rep., 22, 2021
7E6J	Aspartyl/Asparaginyl beta-hydroxylase (AspH) H725A in complex with Factor X peptide fragment (39mer-4Ser) 分子名称: Aspartyl/asparaginyl beta-hydroxylase, GLYCEROL, PROPANOIC ACID, ... 著者 Nakashima, Y, Brasnett, A, Brewitz, L, Schofield, C.J. 登録日 2021-02-22 公開日 2021-06-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Human Oxygenase Variants Employing a Single Protein Fe II Ligand Are Catalytically Active. Angew.Chem.Int.Ed.Engl., 60, 2021

 

123456789101112>