7TPQ
Cryo-em structure of human prothrombinase on a nanodisc at 5.3 Angstrom resolution
Summary for 7TPQ
| Entry DOI | 10.2210/pdb7tpq/pdb |
| EMDB information | 26061 |
| Descriptor | Factor X light chain, Coagulation factor Va, Activated factor Xa heavy chain, ... (4 entities in total) |
| Functional Keywords | prothrombinase, blood clotting |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 200835.38 |
| Authors | Di Cera, E.,Ruben, E.A. (deposition date: 2022-01-25, release date: 2022-05-04, Last modification date: 2022-06-29) |
| Primary citation | Ruben, E.A.,Summers, B.,Rau, M.J.,Fitzpatrick, J.A.J.,Di Cera, E. Cryo-EM structure of the prothrombin-prothrombinase complex. Blood, 139:3463-3473, 2022 Cited by PubMed: 35427420DOI: 10.1182/blood.2022015807 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (5.3 Å) |
Structure validation
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