9CTH

Preliminary map of the Prothrombin-prothrombinase complex on nano discs

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Activated Factor V (FVa) heavy chain	polymer	709	81274.4	1	UniProt (P12259) In PDB	Homo sapiens (human)	Coagulation factor Va heavy chain,Activated protein C cofactor,Proaccelerin,labile factor
2	E	Activated Factor V (FVa) light chain	polymer	651	75283.0	1	UniProt (P12259) In PDB	Homo sapiens (human)	Coagulation factor Va light chain,Activated protein C cofactor,Proaccelerin,labile factor
3	B	Activated Factor X light chain	polymer	142	16187.0	1	UniProt (P00742) In PDB	Homo sapiens (human)	FXa-LC,Factor X light chain
4	C	Activated Factor X heavy chain	polymer	235	26588.3	1	UniProt (P00742) In PDB	Homo sapiens (human)	FXa-HC,Factor X heavy chain
5	D	Prothrombin	polymer	579	65370.1	1	UniProt (P00734) In PDB	Homo sapiens (human)	Coagulation factor II
6	A, E, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)

Sequence modifications

C: 16 - 245 (UniProt: P00742)

PDB	External Database	Details
Ala 195	Ser 419	engineered mutation

D: 1 - 579 (UniProt: P00734)

PDB	External Database	Details
Ala 525	Ser 568	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	264702.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	266030.0

*Water molecules are not included.