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7TPP

Cryo-em structure of human prothrombin:prothrombinase at 4.1 Angstrom resolution

Summary for 7TPP
Entry DOI10.2210/pdb7tpp/pdb
EMDB information26060
DescriptorProthrombin, Factor X light chain, Coagulation factor Va, ... (5 entities in total)
Functional Keywordsprothrombin prothrombinase, blood clotting
Biological sourceHomo sapiens (human)
More
Total number of polymer chains5
Total formula weight266205.49
Authors
Di Cera, E.,Ruben, E.A. (deposition date: 2022-01-25, release date: 2022-05-04, Last modification date: 2022-06-29)
Primary citationRuben, E.A.,Summers, B.,Rau, M.J.,Fitzpatrick, J.A.J.,Di Cera, E.
Cryo-EM structure of the prothrombin-prothrombinase complex.
Blood, 139:3463-3473, 2022
Cited by
PubMed: 35427420
DOI: 10.1182/blood.2022015807
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.1 Å)
Structure validation

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