PDB: 917 resultsInfo pagesStatus searchChemie searchBIRD

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7PCV	Crystal structure of RBM5 RRM1-zinc finger Descriptor: RNA-binding protein 5, ZINC ION Authors: Soni, K, Jagtap, P.K.A, Sattler, M. Deposit date: 2021-08-04 Release date: 2022-08-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Structural basis for specific RNA recognition by the alternative splicing factor RBM5. Nat Commun, 14, 2023
7EVO	The cryo-EM structure of the human 17S U2 snRNP Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... Authors: Zhang, X, Zhan, X, Shi, Y. Deposit date: 2021-05-21 Release date: 2022-08-03 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
7SN6	U2AF65 UHM BOUND TO SF3B155 ULM5 Descriptor: ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit Authors: Loerch, S, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2021-10-27 Release date: 2022-07-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing. J.Biol.Chem., 298, 2022
7QZP	Identification and characterization of an RRM-containing, ELAV-like, RNA binding protein in Acinetobacter Baumannii Descriptor: Hypothetical RNA binding protein from Acinetobacter baumannii Authors: Ciani, C, Perez-Rafols, A, Bonomo, I, Micaelli, M, Esposito, A, Zucal, C, Belli, R, D'Agostino, V.G, Bianconi, I, Calderone, V, Cerofolini, L, Fragai, M, Provenzani, A. Deposit date: 2022-01-31 Release date: 2022-07-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii . Biomolecules, 12, 2022
7UY5	Tetrahymena telomerase with CST Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... Authors: He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. Deposit date: 2022-05-06 Release date: 2022-07-13 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
7UY6	Tetrahymena telomerase at 2.9 Angstrom resolution Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... Authors: He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. Deposit date: 2022-05-06 Release date: 2022-07-13 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
7WM3	hnRNP A2/B1 RRMs in complex with single-stranded DNA Descriptor: DNA (5'-D(P*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoproteins A2/B1 Authors: Abula, A, Liu, Y, Guo, H, Li, T, Ji, X. Deposit date: 2022-01-14 Release date: 2022-06-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition. J.Mol.Biol., 435, 2022
7W5B	The cryo-EM structure of human C* complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2021-11-29 Release date: 2022-06-22 Last modified: 2022-08-17 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7W5A	The cryo-EM structure of human pre-C*-II complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2021-11-29 Release date: 2022-06-22 Last modified: 2022-08-17 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7W59	The cryo-EM structure of human pre-C*-I complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Zhan, X, Lu, Y, Shi, Y. Deposit date: 2021-11-29 Release date: 2022-06-22 Last modified: 2022-08-17 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7S7B	Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ... Authors: Puno, M.R, Lima, C.D. Deposit date: 2021-09-15 Release date: 2022-06-15 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.06 Å) Cite: Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
7S7C	Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2) Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ... Authors: Puno, M.R, Lima, C.D. Deposit date: 2021-09-15 Release date: 2022-06-15 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
7S3B	Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Jenkins, J.L, Henderson, S, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3C	Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Glasser, E, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3A	Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit Authors: Jenkins, J.L, Henderson, S, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7ZEX	Complex Cyp33-RRMdelta alpha : UAAUGUCG RNA Descriptor: Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3') Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-05-04 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7Q4L	The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA Descriptor: Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3') Authors: Duszczyk, M.M, Allain, F.H.T. Deposit date: 2021-10-31 Release date: 2022-05-04 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation. Nat Commun, 13, 2022
7ZEV	Free form of extended Cyp33-RRM Descriptor: Peptidyl-prolyl cis-trans isomerase E Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEW	Complex Cyp33-RRM : AAUAAA RNA Descriptor: Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*AP*AP*UP*AP*AP*A)-3') Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEZ	Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 Descriptor: Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2023-05-03 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEY	Complex Cyp33-RRM : MLL1-PHD3 Descriptor: MLL cleavage product N320, Peptidyl-prolyl cis-trans isomerase E, ZINC ION Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7Q4O	Substrate-bound A-like U2 snRNP Descriptor: BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-11-01 Release date: 2022-03-30 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7Q3L	Human 17S U2 snRNP 5' domain Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-10-28 Release date: 2022-03-30 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.21 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022

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