7ZEX
Complex Cyp33-RRMdelta alpha : UAAUGUCG RNA
Summary for 7ZEX
Entry DOI | 10.2210/pdb7zex/pdb |
NMR Information | BMRB: 34726 |
Descriptor | Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3') (2 entities in total) |
Functional Keywords | rrm, rna binding protein-structural protein complex, histone 3, h3k4me3, epigenetic, mll1 transcription regulation, infant leukemia, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 12877.27 |
Authors | Blatter, M.,Allain, F.,Meylan, C. (deposition date: 2022-03-31, release date: 2022-05-04, Last modification date: 2023-05-03) |
Primary citation | Blatter, M.,Meylan, C.,Clery, A.,Giambruno, R.,Nikolaev, Y.,Heidecker, M.,Solanki, J.A.,Diaz, M.O.,Gabellini, D.,Allain, F.H. RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9:eadf5330-eadf5330, 2023 Cited by PubMed: 37075125DOI: 10.1126/sciadv.adf5330 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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