7Q4L
The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA
Summary for 7Q4L
Entry DOI | 10.2210/pdb7q4l/pdb |
NMR Information | BMRB: 34675 |
Descriptor | Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3') (2 entities in total) |
Functional Keywords | protein-rna complex, post-transcriptional gene regulation, ptgr, germ line differentiation, au-rich rna binding protein, rna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 27393.40 |
Authors | Duszczyk, M.M.,Allain, F.H.T. (deposition date: 2021-10-31, release date: 2022-05-04, Last modification date: 2024-06-19) |
Primary citation | Duszczyk, M.M.,Wischnewski, H.,Kazeeva, T.,Arora, R.,Loughlin, F.E.,von Schroetter, C.,Pradere, U.,Hall, J.,Ciaudo, C.,Allain, F.H. The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation. Nat Commun, 13:5892-5892, 2022 Cited by PubMed: 36202814DOI: 10.1038/s41467-022-33552-x PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report