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7Q4L

The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA

Summary for 7Q4L
Entry DOI10.2210/pdb7q4l/pdb
NMR InformationBMRB: 34675
DescriptorDead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3') (2 entities in total)
Functional Keywordsprotein-rna complex, post-transcriptional gene regulation, ptgr, germ line differentiation, au-rich rna binding protein, rna binding protein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains2
Total formula weight27393.40
Authors
Duszczyk, M.M.,Allain, F.H.T. (deposition date: 2021-10-31, release date: 2022-05-04, Last modification date: 2024-06-19)
Primary citationDuszczyk, M.M.,Wischnewski, H.,Kazeeva, T.,Arora, R.,Loughlin, F.E.,von Schroetter, C.,Pradere, U.,Hall, J.,Ciaudo, C.,Allain, F.H.
The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.
Nat Commun, 13:5892-5892, 2022
Cited by
PubMed: 36202814
DOI: 10.1038/s41467-022-33552-x
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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