7Q4L

The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA

Summary for 7Q4L

• Entry DOI: 10.2210/pdb7q4l/pdb
• NMR Information: BMRB: 34675
• Descriptor: Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3') (2 entities in total)
• Functional Keywords: protein-rna complex, post-transcriptional gene regulation, ptgr, germ line differentiation, au-rich rna binding protein, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27393.40

Authors

Duszczyk, M.M.,Allain, F.H.T. (deposition date: 2021-10-31, release date: 2022-05-04, Last modification date: 2024-06-19)

• Primary citation: Duszczyk, M.M.,Wischnewski, H.,Kazeeva, T.,Arora, R.,Loughlin, F.E.,von Schroetter, C.,Pradere, U.,Hall, J.,Ciaudo, C.,Allain, F.H.; The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation.; Nat Commun, 13:5892-5892, 2022; PubMed: 36202814; DOI: 10.1038/s41467-022-33552-x

Experimental method

SOLUTION NMR