7SN6

U2AF65 UHM BOUND TO SF3B155 ULM5

Summary for 7SN6

Entry DOI	10.2210/pdb7sn6/pdb
Descriptor	Splicing factor U2AF 65 kDa subunit, Splicing factor 3B subunit 1, ISOPROPYL ALCOHOL, ... (4 entities in total)
Functional Keywords	u2af homology motif, uhm, pre-mrna splicing factor, protein binding, phosphorylation, protein-peptide complex, splicing, peptide binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	28498.31
Authors	Loerch, S.,Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2021-10-27, release date: 2022-07-27, Last modification date: 2023-10-18)
Primary citation	Galardi, J.W.,Bela, V.N.,Jeffery, N.,He, X.,Glasser, E.,Loerch, S.,Jenkins, J.L.,Pulvino, M.J.,Boutz, P.L.,Kielkopf, C.L. A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing. J.Biol.Chem., 298:102224-102224, 2022 Cited by PubMed: 35780835 DOI: 10.1016/j.jbc.2022.102224 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation