7QP7

Structure of the human 48S initiation complex in closed state (h48S AUG closed)

This is a non-PDB format compatible entry.

Summary for 7QP7

• Entry DOI: 10.2210/pdb7qp7/pdb
• EMDB information: 14114
• Descriptor: Eukaryotic translation initiation factor 3 subunit B, 40S ribosomal protein S11, 40S ribosomal protein S4, X isoform, ... (52 entities in total)
• Functional Keywords: 48s, initiation, eif3, ternary complex, translation, open state, ribosome
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 51
• Total formula weight: 2165279.14

Authors

Yi, S.-H.,Petrychenko, V.,Schliep, J.E.,Goyal, A.,Linden, A.,Chari, A.,Urlaub, H.,Stark, H.,Rodnina, M.V.,Adio, S.,Fischer, N. (deposition date: 2022-01-03, release date: 2022-05-11, Last modification date: 2022-06-01)

• Primary citation: Yi, S.H.,Petrychenko, V.,Schliep, J.E.,Goyal, A.,Linden, A.,Chari, A.,Urlaub, H.,Stark, H.,Rodnina, M.V.,Adio, S.,Fischer, N.; Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.; Nucleic Acids Res., 50:5282-5298, 2022; PubMed: 35489072; DOI: 10.1093/nar/gkac283

Experimental method

ELECTRON MICROSCOPY (3.7 Å)