7S7B
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Summary for 7S7B
Entry DOI | 10.2210/pdb7s7b/pdb |
EMDB information | 24882 |
Descriptor | Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8,Zinc finger CCHC domain-containing protein 8, RNA-binding protein 7, ... (5 entities in total) |
Functional Keywords | helicase, atpase, rna, exosome, rna binding protein, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 423237.96 |
Authors | Puno, M.R.,Lima, C.D. (deposition date: 2021-09-15, release date: 2022-06-15, Last modification date: 2024-06-05) |
Primary citation | Puno, M.R.,Lima, C.D. Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185:2132-2147.e26, 2022 Cited by PubMed: 35688134DOI: 10.1016/j.cell.2022.04.016 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.06 Å) |
Structure validation
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