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5C5T
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The crystal structure of viral collagen prolyl hydroxylase vCPH from Paramecium Bursaria Chlorella virus-1 - 2OG complex
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, Prolyl 4-hydroxylase, ...
Authors:Levy, C.W.
Deposit date:2015-06-22
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase.
Biochemistry, 54, 2015
5C5U
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The crystal structure of viral collagen prolyl hydroxylase vCPH from Paramecium Bursaria Chlorella virus-1 - Truncated Construct
Descriptor: ACETATE ION, MANGANESE (II) ION, Prolyl 4-hydroxylase, ...
Authors:Longbotham, J.E, Levy, C.W, Johannisen, L.O, Tarhonskaya, H, Jiang, S, Loenarz, C, Flashman, E, Hay, S, Schofiled, C.J, Scrutton, N.S.
Deposit date:2015-06-22
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase.
Biochemistry, 54, 2015
5CEZ
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Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with an early putative precursor of the PGT121 family at 3.0 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Fab Heavy Chain, ...
Authors:Wilson, I.A, Garces, F.
Deposit date:2015-07-08
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.031 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
7QU1
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Machupo virus GP1 glycoprotein in complex with Fab fragment of antibody MAC1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab MAC1 heavy chain, Fab MAC1 light chain, ...
Authors:Ng, W.M, Sahin, M, Krumm, S.A, Seow, J, Zeltina, A, Harlos, K, Paesen, G, Pinschewer, D.D, Doores, K.J, Bowden, T.A.
Deposit date:2022-01-17
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies.
Mbio, 13, 2022
5CJQ
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Crystal structure of a trimeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: CR9114 heavy chain, CR9114 light chain, Designed influenza hemagglutinin stem #4900, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-14
Release date:2015-09-09
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
5C3T
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PD-1 binding domain from human PD-L1
Descriptor: Programmed cell death 1 ligand 1
Authors:Zak, K.M, Dubin, G, Holak, T.A.
Deposit date:2015-06-17
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.
Structure, 23, 2015
7QBC
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Structure of the GPCR dimer Ste2 in the inactive-like state bound to agonist
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha factor pheromone, CHOLESTEROL HEMISUCCINATE, ...
Authors:Velazhahan, V, Tate, C.G.
Deposit date:2021-11-18
Release date:2022-03-16
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Activation mechanism of the class D fungal GPCR dimer Ste2.
Nature, 603, 2022
7QB9
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Structure of the ligand-free GPCR dimer Ste2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Pheromone alpha factor receptor
Authors:Velazhahan, V, Tate, C.G.
Deposit date:2021-11-18
Release date:2022-03-16
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Activation mechanism of the class D fungal GPCR dimer Ste2.
Nature, 603, 2022
7QBI
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Structure of the GPCR dimer Ste2 in the active-like state bound to agonist
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha factor pheromone, CHOLESTEROL HEMISUCCINATE, ...
Authors:Velazhahan, V, Tate, C.G.
Deposit date:2021-11-19
Release date:2022-03-16
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Activation mechanism of the class D fungal GPCR dimer Ste2.
Nature, 603, 2022
7QA8
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Structure of the GPCR dimer Ste2 bound to an antagonist
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, HIS-ALA-LEU-GLN-LEU-LYS-PRO-GLY-GLN-PRO-NLE-TYR, ...
Authors:Velazhahan, V, Tate, C.G.
Deposit date:2021-11-16
Release date:2022-03-16
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Activation mechanism of the class D fungal GPCR dimer Ste2.
Nature, 603, 2022
7QNE
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Cryo-EM structure of human full-length synaptic alpha1beta3gamma2 GABA(A)R in complex with Ro15-4513 and megabody Mb38
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R.
Deposit date:2021-12-20
Release date:2022-04-13
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Differential assembly diversifies GABA A receptor structures and signalling.
Nature, 604, 2022
5CJS
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Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 heavy chain, CR9114 light chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-15
Release date:2015-09-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
5CJX
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Crystal structure of 8ANC195 Fab in complex with BG505 SOSIP.664 HIV-1 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 heavy chain, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2015-07-15
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.584 Å)
Cite:Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
5ACO
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BU of 5aco by Molmil
Cryo-EM structure of PGT128 Fab in complex with BG505 SOSIP.664 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 ENVELOPE GLYCOPROTEIN, ...
Authors:Lee, J.H, Ward, A.B.
Deposit date:2015-08-17
Release date:2015-09-30
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.36 Å)
Cite:Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy.
Structure, 23, 2015
5A3P
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BU of 5a3p by Molmil
Crystal structure of the catalytic domain of human PLU1 (JARID1B).
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, LYSINE-SPECIFIC DEMETHYLASE 5B, ...
Authors:Nowak, R, Srikannathasan, V, Johansson, C, Gileadi, C, Tallant, C, Kupinska, K, Strain-Damerell, C, Szykowska, A, von Delft, F, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U.
Deposit date:2015-06-02
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.008 Å)
Cite:Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Nat.Chem.Biol., 12, 2016
7QUO
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BU of 7quo by Molmil
FimH lectin domain in complex with oligomannose-6
Descriptor: FimH, NICKEL (II) ION, SULFATE ION, ...
Authors:Bouckaert, J, Bourenkov, G.P.
Deposit date:2022-01-18
Release date:2023-02-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors
J.Biol.Chem., 299, 2023
5DJA
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Fc Heterodimer Design 9.1 Y407M + T366I
Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B.
Deposit date:2015-09-01
Release date:2016-03-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
5DI8
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Fc Knob-Hole Heterodimer T366W + T366S/L368A/Y407V
Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Secrist, E, Demarest, S.J, Kuhlman, B.
Deposit date:2015-08-31
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
5DJ0
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Fc Heterodimer Design 11.2 Y349S/K370Y + E357D/S364Q
Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B.
Deposit date:2015-09-01
Release date:2016-03-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
5D4Q
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Crystal structure of GASDALIE IgG1 Fc
Descriptor: Ig gamma-1 chain C region, alpha-L-fucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ahmed, A.A, Bjorkman, P.J.
Deposit date:2015-08-08
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016
5D9M
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Crystal structure of PbGH5A, a glycoside hydrolase family 5 enzyme from Prevotella bryantii B14, E280A mutant in complex with the xyloglucan tetradecasaccharide XXXGXXXG
Descriptor: B-1,4-endoglucanase, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Morar, M, Stogios, P.J, Xu, X, Cui, H, Di Leo, R, Yim, V, Savchenko, A.
Deposit date:2015-08-18
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14.
J.Biol.Chem., 291, 2016
5DJ2
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Fc Heterodimer Design 7.4 Y407A + T366V/K409V
Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Secrist, E, Demarest, S.J, Kuhlman, B.
Deposit date:2015-09-01
Release date:2016-03-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
5DJD
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Fc Heterodimer Design 5.1 T366V + Y407F
Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B.
Deposit date:2015-09-02
Release date:2016-03-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24, 2016
7R81
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Structure of the translating Neurospora crassa ribosome arrested by cycloheximide
Descriptor: 18S rRNA, 26S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Shen, L, Su, Z, Yang, K, Wu, C, Becker, T, Bell-Pedersen, D, Zhang, J, Sachs, M.S.
Deposit date:2021-06-25
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the translating Neurospora ribosome arrested by cycloheximide
Proc.Natl.Acad.Sci.USA, 118, 2021
5AY8
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Crystal structure of human nucleosome containing H3.Y
Descriptor: CHLORIDE ION, DNA (146-MER), H3.Y, ...
Authors:Kujirai, T, Horikoshi, N, Sato, K, Maehara, K, Machida, S, Osakabe, A, Kimura, H, Ohkawa, Y, Kurumizaka, H.
Deposit date:2015-08-10
Release date:2016-04-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and function of human histone H3.Y nucleosome
Nucleic Acids Res., 44, 2016

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