Fc Heterodimer Design 5.1 T366V + Y407F

Summary for 5DJD

Related5DI8 5DJ0 5DJ2 5DJ6 5DJ8 5DJA 5DJC 5DJX 5DJY 5DJZ 5DK0 5DK2
DescriptorIg gamma-1 chain C region, Fc-III peptide, N-ACETYL-D-GLUCOSAMINE, ... (9 entities in total)
Functional Keywordsheterodimer, immunoglobulin, ch3, fc, bispecific antibody, immune system
Biological sourceHomo sapiens (Human)
Cellular locationSecreted P01857 P01857
Total number of polymer chains3
Total molecular weight57207.91
Primary citation
Leaver-Fay, A.,Froning, K.J.,Atwell, S.,Aldaz, H.,Pustilnik, A.,Lu, F.,Huang, F.,Yuan, R.,Hassanali, S.,Chamberlain, A.K.,Fitchett, J.R.,Demarest, S.J.,Kuhlman, B.
Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24:641-651, 2016
PubMed: 26996964 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2016.02.013
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.279301.3%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution