5DJA

Fc Heterodimer Design 9.1 Y407M + T366I

Summary for 5DJA

Related5DI8 5DJ0 5DJ2 5DJ6 5DJ8 5DJC 5DJD 5DJX 5DJY 5DJZ 5DK0 5DK2 5DVK 5DVL 5DVM 5DVN 5DVO
DescriptorIg gamma-1 chain C region, Fc-III peptide, N-ACETYL-D-GLUCOSAMINE, ... (9 entities in total)
Functional Keywordsheterodimer, immunoglobulin, ch3, fc, bispecific antibody, immune system
Biological sourceHomo sapiens (Human)
More
Cellular locationSecreted P01857 P01857
Total number of polymer chains3
Total molecular weight57205.96
Authors
Primary citation
Leaver-Fay, A.,Froning, K.J.,Atwell, S.,Aldaz, H.,Pustilnik, A.,Lu, F.,Huang, F.,Yuan, R.,Hassanali, S.,Chamberlain, A.K.,Fitchett, J.R.,Demarest, S.J.,Kuhlman, B.
Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Structure, 24:641-651, 2016
PubMed: 26996964 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2016.02.013
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.28471.2%4.4%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution