5DVK

Fc Design 7.7 B chain homodimer T366V/K409I

Summary for 5DVK

• Entry DOI: 10.2210/pdb5dvk/pdb
• Related: 5DI8 5DJ0 5DJ2 5DJ6 5DJ8 5DJA 5DJC 5DJD 5DJX 5DJY 5DJZ 5DK0 5DK2 5DVL 5DVM 5DVN 5DVO
• Descriptor: Ig gamma-1 chain C region (3 entities in total)
• Functional Keywords: head-to-tail homodimer, immunoglobulin, fc, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P01857
• Total number of polymer chains: 2
• Total formula weight: 27128.77

Authors

Atwell, S.,Leaver-Fay, A.,Froning, K.J.,Aldaz, H.,Pustilnik, A.,Lu, F.,Huang, F.,Yuan, R.,Dhanani, S.H.,Chamberlain, A.K.,Fitchett, J.R.,Gutierrez, B.,Hendle, J.,Demarest, S.J.,Kuhlman, B. (deposition date: 2015-09-21, release date: 2016-03-30, Last modification date: 2016-04-27)

• Primary citation: Leaver-Fay, A.,Froning, K.J.,Atwell, S.,Aldaz, H.,Pustilnik, A.,Lu, F.,Huang, F.,Yuan, R.,Hassanali, S.,Chamberlain, A.K.,Fitchett, J.R.,Demarest, S.J.,Kuhlman, B.; Computationally Designed Bispecific Antibodies using Negative State Repertoires.; Structure, 24:641-651, 2016; PubMed: 26996964; DOI: 10.1016/j.str.2016.02.013

Experimental method

X-RAY DIFFRACTION (2.6 Å)