5DVK
Fc Design 7.7 B chain homodimer T366V/K409I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ig gamma-1 chain C region | polymer | 227 | 25595.0 | 1 | UniProt (P01857) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B (B) | Ig gamma-1 chain C region | polymer | 13 | 1533.7 | 1 | synthetic construct | ||
| 3 | C, D (A, B) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 221 - 447 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Glu 356 | Asp 239 | variant |
| Met 358 | Leu 241 | variant |
| Val 366 | Thr 249 | engineered mutation |
| Ile 409 | Lys 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27128.8 | |
| All* | Total formula weight | 27128.8 |
