7QA8

Structure of the GPCR dimer Ste2 bound to an antagonist

Summary for 7QA8

Entry DOI	10.2210/pdb7qa8/pdb
EMDB information	13880
Descriptor	Pheromone alpha factor receptor, HIS-ALA-LEU-GLN-LEU-LYS-PRO-GLY-GLN-PRO-NLE-TYR, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	gpcr, dimer, antagonist-bound, fungal, membrane protein
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Total number of polymer chains	4
Total formula weight	115937.53
Authors	Velazhahan, V.,Tate, C.G. (deposition date: 2021-11-16, release date: 2022-03-16, Last modification date: 2022-04-06)
Primary citation	Velazhahan, V.,Ma, N.,Vaidehi, N.,Tate, C.G. Activation mechanism of the class D fungal GPCR dimer Ste2. Nature, 603:743-748, 2022 Cited by PubMed: 35296853 DOI: 10.1038/s41586-022-04498-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation