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7QA8

Structure of the GPCR dimer Ste2 bound to an antagonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, B)
Pheromone alpha factor receptorpolymer43147885.42UniProt (P0CI39)
Pfam (PF02116)
UniProt (by SIFTS) (D6VTK4)
Saccharomyces cerevisiae (Baker's yeast)
2B, C
(K, I)
HIS-ALA-LEU-GLN-LEU-LYS-PRO-GLY-GLN-PRO-NLE-TYRpolymer121366.62Pfam (PF04648)
UniProt (by SIFTS) (P01149)
Saccharomyces cerevisiae
3E, F, X, Y
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
4AA, BA, CA, DA, EA...
(B, A, I)
CHOLESTEROL HEMISUCCINATEnon-polymer486.734Chemie (Y01)
5QA, RA, SA, TA
(A, K, I, B)
waterwater18.070Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight98504.0
Non-Polymers*Number of molecules38
Total formula weight17433.5
All*Total formula weight115937.5
*Water molecules are not included.

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PDB entries from 2025-10-29

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