5CJS
Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Summary for 5CJS
Entry DOI | 10.2210/pdb5cjs/pdb |
Related | 5CJQ |
Descriptor | CR9114 light chain, CR9114 heavy chain, Designed influenza hemagglutinin stem #4454, HA1, ... (5 entities in total) |
Functional Keywords | hemagglutinin, trimer, influenza, immunogen, monoclonal, antibody, neutralizing, influenza vaccine, glycoprotein, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 152111.59 |
Authors | Zhu, X.,Wilson, I.A. (deposition date: 2015-07-15, release date: 2015-09-09, Last modification date: 2020-07-29) |
Primary citation | Impagliazzo, A.,Milder, F.,Kuipers, H.,Wagner, M.V.,Zhu, X.,Hoffman, R.M.,van Meersbergen, R.,Huizingh, J.,Wanningen, P.,Verspuij, J.,de Man, M.,Ding, Z.,Apetri, A.,Kukrer, B.,Sneekes-Vriese, E.,Tomkiewicz, D.,Laursen, N.S.,Lee, P.S.,Zakrzewska, A.,Dekking, L.,Tolboom, J.,Tettero, L.,van Meerten, S.,Yu, W.,Koudstaal, W.,Goudsmit, J.,Ward, A.B.,Meijberg, W.,Wilson, I.A.,Radosevic, K. A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen. Science, 349:1301-1306, 2015 Cited by PubMed: 26303961DOI: 10.1126/science.aac7263 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.3 Å) |
Structure validation
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