5D4Q

Crystal structure of GASDALIE IgG1 Fc

Summary for 5D4Q

• Entry DOI: 10.2210/pdb5d4q/pdb
• Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose, ... (4 entities in total)
• Functional Keywords: adcc, igg fc, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 53057.30

Authors

Ahmed, A.A.,Bjorkman, P.J. (deposition date: 2015-08-08, release date: 2016-02-10, Last modification date: 2023-09-27)

• Primary citation: Ahmed, A.A.,Keremane, S.R.,Vielmetter, J.,Bjorkman, P.J.; Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.; J.Struct.Biol., 194:78-89, 2016; PubMed: 26850169; DOI: 10.1016/j.jsb.2016.02.001

Experimental method

X-RAY DIFFRACTION (2.39 Å)