5D4Q
Crystal structure of GASDALIE IgG1 Fc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Ig gamma-1 chain C region | polymer | 221 | 24967.2 | 2 | UniProt (P01857) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 2 | C, D | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1479.3 | 2 | In PDB GlyTouCan (G89993FE) | |||
| 3 | B | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 4 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B: 226 - 446 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Ala 236 | Gly 119 | engineered mutation |
| Asp 239 | Ser 122 | engineered mutation |
| Leu 330 | Ala 213 | engineered mutation |
| Glu 332 | Ile 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49934.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2958.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 164.2 | |
| All* | Total formula weight | 53057.3 |
