7QBI

Structure of the GPCR dimer Ste2 in the active-like state bound to agonist

Summary for 7QBI

Entry DOI	10.2210/pdb7qbi/pdb
Related	7QA8 7QB9 7QBC
EMDB information	13880 13882 13886 13887
Descriptor	Pheromone alpha factor receptor, Alpha factor pheromone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	gpcr, dimer, agonist-bound, fungal, membrane protein
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Total number of polymer chains	4
Total formula weight	105868.32
Authors	Velazhahan, V.,Tate, C.G. (deposition date: 2021-11-19, release date: 2022-03-16, Last modification date: 2022-04-06)
Primary citation	Velazhahan, V.,Ma, N.,Vaidehi, N.,Tate, C.G. Activation mechanism of the class D fungal GPCR dimer Ste2. Nature, 603:743-748, 2022 Cited by PubMed: 35296853 DOI: 10.1038/s41586-022-04498-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.46 Å)

Structure validation