7QA8
Structure of the GPCR dimer Ste2 bound to an antagonist
Summary for 7QA8
Entry DOI | 10.2210/pdb7qa8/pdb |
EMDB information | 13880 |
Descriptor | Pheromone alpha factor receptor, HIS-ALA-LEU-GLN-LEU-LYS-PRO-GLY-GLN-PRO-NLE-TYR, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | gpcr, dimer, antagonist-bound, fungal, membrane protein |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 4 |
Total formula weight | 115937.53 |
Authors | Velazhahan, V.,Tate, C.G. (deposition date: 2021-11-16, release date: 2022-03-16, Last modification date: 2024-10-16) |
Primary citation | Velazhahan, V.,Ma, N.,Vaidehi, N.,Tate, C.G. Activation mechanism of the class D fungal GPCR dimer Ste2. Nature, 603:743-748, 2022 Cited by PubMed: 35296853DOI: 10.1038/s41586-022-04498-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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