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8JT0
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BU of 8jt0 by Molmil
Dihydrofolate reductase-like enzyme from Leptospira interrogans with additional NADP+
Descriptor: ACETATE ION, Dihydrofolate reductase family protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Wangkanont, K.
Deposit date:2023-06-20
Release date:2024-06-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Dihydrofolate reductase-like enzyme from Leptospira interrogans with additional NADP+
To Be Published
4P0F
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BU of 4p0f by Molmil
Cleaved Serpin 42Da (C 2 2 21)
Descriptor: Serine protease inhibitor 4, isoform B
Authors:Ellisdon, A.M, Whisstock, J.C.
Deposit date:2014-02-21
Release date:2014-05-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster.
Bmc Struct.Biol., 14, 2014
4KC1
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BU of 4kc1 by Molmil
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Descriptor: 6-(1-beta-D-Glucopyranosyloxymethyl)-N-(5'-deoxyluridine-5'-yl)picolinamide, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, MANGANESE (II) ION, ...
Authors:Cuesta-Seijo, J.A, Wang, S, Lafont, D, Vidal, S, Palcic, M.M.
Deposit date:2013-04-24
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate.
Chemistry, 19, 2013
4KC2
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BU of 4kc2 by Molmil
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Descriptor: 6-(1-beta-D-Galactopyranosyloxymethyl)-N-(5'-deoxyluridine-5'-yl)picolinamide, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form, MANGANESE (II) ION, ...
Authors:Cuesta-Seijo, J.A, Wang, S, Lafont, D, Vidal, S, Palcic, M.M.
Deposit date:2013-04-24
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate.
Chemistry, 19, 2013
4GD7
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BU of 4gd7 by Molmil
Wild-Type Human Thymidylate Synthase with bound Purpurogallin
Descriptor: 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, SULFATE ION, ...
Authors:Celeste, L.R, Lebioda, L.
Deposit date:2012-07-31
Release date:2013-07-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin
To be published, 2012
5WRO
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BU of 5wro by Molmil
Crystal structure of Drosophila enolase
Descriptor: CADMIUM ION, CHLORIDE ION, COBALT (II) ION, ...
Authors:Zhang, Z, Shi, Z.
Deposit date:2016-12-02
Release date:2017-04-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.015 Å)
Cite:Crystal structure of enolase from Drosophila melanogaster.
Acta Crystallogr F Struct Biol Commun, 73, 2017
7ZXK
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BU of 7zxk by Molmil
Human IL-27 in complex with neutralizing SRF388 FAb fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ...
Authors:Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N.
Deposit date:2022-05-21
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
6LLQ
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BU of 6llq by Molmil
Solution NMR structure of de novo Rossmann2x2 fold with most of the core mutated to valine, R2x2_VAL88
Descriptor: VAL88
Authors:Kobayashi, N, Sugiki, T, Fujiwara, T, Koga, R, Yamamoto, M, Kosugi, T, Koga, N.
Deposit date:2019-12-23
Release date:2020-12-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Robust folding of a de novo designed ideal protein even with most of the core mutated to valine.
Proc.Natl.Acad.Sci.USA, 117, 2020
8DC1
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BU of 8dc1 by Molmil
Structural and biochemical characterization of L. interrogans Lsa45 reveals a penicillin-binding protein with esterase activity
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IODIDE ION, ...
Authors:Santos, J.C, Nascimento, A.L.T.O.
Deposit date:2022-06-15
Release date:2023-01-11
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and biochemical characterization of Leptospira interrogans Lsa45 reveals a penicillin-binding protein with esterase activity.
Process Biochem, 125, 2023
5WOU
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BU of 5wou by Molmil
Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with Guk-Holder
Descriptor: 1,2-ETHANEDIOL, GUK-holder, isoform A, ...
Authors:Caria, S, Kvansakul, M.
Deposit date:2017-08-03
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large.
J. Biol. Chem., 293, 2018
4KC4
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BU of 4kc4 by Molmil
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Descriptor: 5'-deoxy-5'-[({6-[(alpha-D-galactopyranosyloxy)methyl]pyridin-2-yl}carbonyl)amino]uridine, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, MANGANESE (II) ION, ...
Authors:Cuesta-Seijo, J.A, Wang, S, Lafont, D, Vidal, S, Palcic, M.M.
Deposit date:2013-04-24
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate.
Chemistry, 19, 2013
8EBF
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BU of 8ebf by Molmil
C-terminal (TPR) domain of LIC11990 from Leptospira interrogans
Descriptor: ACETATE ION, Cytoplasmic membrane protein, GLYCEROL
Authors:Larrieux, N, Buschiazzo, A.
Deposit date:2022-08-31
Release date:2022-09-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and function of a novel membrane-associated protein from Leptospira interrogans (gene LIC11990)
To Be Published
6ULO
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BU of 6ulo by Molmil
Structure of an N-terminally truncated uncharacterized protein from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Copenhageni (strain Fiocruz L1-130)
Descriptor: CHLORIDE ION, Uncharacterized protein
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-10-08
Release date:2019-10-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of an N-terminally truncated uncharacterized protein from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Copenhageni (strain Fiocruz L1-130)
to be published
4QRI
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BU of 4qri by Molmil
2.35 Angstrom resolution crystal structure of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Descriptor: DI(HYDROXYETHYL)ETHER, Hypoxanthine-guanine-xanthine phosphoribosyltransferase, SULFATE ION
Authors:Halavaty, A.S, Minasov, G, Dubrovska, I, Flores, K.J, Shuvalova, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-07-01
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2.35 Angstrom resolution crystal structure of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
To be Published
5NL9
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BU of 5nl9 by Molmil
Crystal structure of a peroxide stress regulator from Leptospira interrogans
Descriptor: POTASSIUM ION, Transcriptional regulator (FUR family), UNKNOWN ATOM OR ION, ...
Authors:Saul, F.A, Haouz, A, Picardeau, M, Benaroudj, N.
Deposit date:2017-04-04
Release date:2017-11-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and function of the Leptospira interrogans peroxide stress regulator (PerR), an atypical PerR devoid of a structural metal-binding site.
J. Biol. Chem., 293, 2018
4ZXO
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BU of 4zxo by Molmil
The structure of a GH26 beta-mannanase from Bacteroides ovatus, BoMan26A.
Descriptor: Glycosyl hydrolase family 26, PHOSPHATE ION, POTASSIUM ION
Authors:Bagenholm, V, Aurelius, O, Logan, D.T, Bouraoui, H, Stalbrand, H.
Deposit date:2015-05-20
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Galactomannan Catabolism Conferred by a Polysaccharide Utilization Locus of Bacteroides ovatus: ENZYME SYNERGY AND CRYSTAL STRUCTURE OF A beta-MANNANASE.
J. Biol. Chem., 292, 2017
4G2O
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BU of 4g2o by Molmil
Human Thymidylate Synthase M190K with bound Purpurogallin
Descriptor: 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, SULFATE ION, Thymidylate synthase
Authors:Celeste, L.R, Lebioda, L.
Deposit date:2012-07-12
Release date:2013-07-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin
To be Published
4G3A
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BU of 4g3a by Molmil
Crystal Structure of MAST/Orbit N-terminal domain
Descriptor: CLIP-associating protein, GLYCEROL
Authors:De la Mora-Rey, T.
Deposit date:2012-07-13
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:The structure of the TOG-like domain of Drosophila melanogaster Mast/Orbit.
Acta Crystallogr.,Sect.F, 69, 2013
5F6A
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BU of 5f6a by Molmil
Drosophila Melanogaster Cycle W398A PAS-B with Empty Pocket
Descriptor: Protein cycle
Authors:Manahan, C.C, Crane, B.R.
Deposit date:2015-12-05
Release date:2016-12-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Drosophila Melanogaster Cycle PAS-B
To Be Published
5F69
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BU of 5f69 by Molmil
Drosophila Melanogaster Cycle W398A PAS-B with Bound Glycerol
Descriptor: GLYCEROL, Protein cycle
Authors:Manahan, C.C, Crane, B.R.
Deposit date:2015-12-05
Release date:2016-12-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.374 Å)
Cite:Drosophila Melanogaster Cycle PAS-B with Bound Glycerol
To Be Published
4LNV
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BU of 4lnv by Molmil
Crystal Structure of TEP1s
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thioester-containing protein I
Authors:Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G.
Deposit date:2013-07-12
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural analysis of TEP1 susceptible and resistant alleles.
Plos Pathog., 8, 2012
5F68
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BU of 5f68 by Molmil
Drosophila Melanogaster Cycle W398A PAS-B with Bound Ethylene Glycol
Descriptor: 1,2-ETHANEDIOL, Protein cycle
Authors:Manahan, C.C, Crane, B.R.
Deposit date:2015-12-05
Release date:2016-12-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Drosophila Melanogaster Cycle PAS-B with Bound Ethylene Glycol
To Be Published
7UVE
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BU of 7uve by Molmil
Drosophila melanogaster setdb1-tuor domain with peptide H3K9me2K14ac
Descriptor: Histone-lysine N-methyltransferase eggless, peptide H3K9me2K14ac
Authors:Zhou, M, Dong, A, Liu, K, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2022-05-01
Release date:2022-08-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Drosophila melanogaster setdb1-tuor domain with peptide H3K9me2K14ac
To Be Published
7UW8
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BU of 7uw8 by Molmil
Drosophila melanogaster setdb1-tuor domain
Descriptor: Histone-lysine N-methyltransferase eggless
Authors:Zhou, M, Dong, A, Liu, K, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2022-05-03
Release date:2022-08-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Drosophila melanogaster setdb1-tuor domain
To Be Published
4NT4
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BU of 4nt4 by Molmil
Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster
Descriptor: GLYCEROL, Gilgamesh, isoform I, ...
Authors:Chen, C.C, Shi, Z.B, Zhou, Z.C.
Deposit date:2013-11-30
Release date:2014-04-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure of the kinase domain of Gilgamesh from Drosophila melanogaster
Acta Crystallogr.,Sect.F, 70, 2014

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