4G2O
Human Thymidylate Synthase M190K with bound Purpurogallin
Summary for 4G2O
Entry DOI | 10.2210/pdb4g2o/pdb |
Related | 3EGY 3EHI 4G6W 4GD7 |
Descriptor | Thymidylate synthase, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, SULFATE ION, ... (4 entities in total) |
Functional Keywords | methyltransferase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P04818 |
Total number of polymer chains | 1 |
Total formula weight | 36281.34 |
Authors | Celeste, L.R.,Lebioda, L. (deposition date: 2012-07-12, release date: 2013-07-17, Last modification date: 2023-09-13) |
Primary citation | Celeste, L.R.,Lovelace, L.L.,Lebioda, L. Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin To be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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