4G2O
Human Thymidylate Synthase M190K with bound Purpurogallin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X | Thymidylate synthase | polymer | 313 | 35869.0 | 1 | UniProt (P04818) Pfam (PF00303) In PDB | Homo sapiens (human) | TS, TSase |
2 | X | 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | non-polymer | 220.2 | 1 | Chemie (TIY) | |||
3 | X | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
X: 1 - 313 (UniProt: P04818)
PDB | External Database | Details |
---|---|---|
Lys 190 | Met 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35869.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 412.3 | |
All* | Total formula weight | 36281.3 |