4GD7
Wild-Type Human Thymidylate Synthase with bound Purpurogallin
Summary for 4GD7
Entry DOI | 10.2210/pdb4gd7/pdb |
Related | 3EHI 4G2O 4G6W |
Descriptor | Thymidylate Synthase, 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, ... (5 entities in total) |
Functional Keywords | methyltransferase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P04818 |
Total number of polymer chains | 1 |
Total formula weight | 36517.60 |
Authors | Celeste, L.R.,Lebioda, L. (deposition date: 2012-07-31, release date: 2013-07-31, Last modification date: 2023-09-13) |
Primary citation | Lesa, C.R.,Leslie, L.L.,Lukasz, L. Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin To be published, 2012 |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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