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8B3F
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BU of 8b3f by Molmil
Pol II-CSB-CSA-DDB1-ELOF1
Descriptor: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2022-09-16
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Pol II-CSB-CSA-DDB1-ELOF1 structure.
To Be Published
8B3D
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BU of 8b3d by Molmil
Structure of the Pol II-TCR-ELOF1 complex.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2022-09-16
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of the Pol II-TCR-ELOF1 complex.
To Be Published
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6AHD
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BU of 6ahd by Molmil
The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
Authors:Zhan, X, Yan, C, Zhang, X, Shi, Y.
Deposit date:2018-08-17
Release date:2018-11-14
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
6AH0
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BU of 6ah0 by Molmil
The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Zhan, X, Yan, C, Zhang, X, Shi, Y.
Deposit date:2018-08-15
Release date:2018-11-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
8H6J
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BU of 8h6j by Molmil
Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y.
Deposit date:2022-10-18
Release date:2024-05-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6E
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BU of 8h6e by Molmil
Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
Deposit date:2022-10-17
Release date:2024-05-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6K
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BU of 8h6k by Molmil
Cryo-EM structure of human exon-defined spliceosome in the mature B state.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
Deposit date:2022-10-18
Release date:2024-05-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
6TBM
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BU of 6tbm by Molmil
Structure of SAGA bound to TBP, including Spt8 and DUB
Descriptor: Polyubiquitin-B, SAGA-associated factor 11, Spt20, ...
Authors:Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A.
Deposit date:2019-11-01
Release date:2020-02-12
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Structure of SAGA and mechanism of TBP deposition on gene promoters.
Nature, 577, 2020
8H6L
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BU of 8h6l by Molmil
Cryo-EM structure of human exon-defined spliceosome in the early B state.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
Deposit date:2022-10-18
Release date:2024-05-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
5Z58
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BU of 5z58 by Molmil
Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
6HCJ
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BU of 6hcj by Molmil
Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6QX9
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BU of 6qx9 by Molmil
Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Charenton, C, Wilkinson, M.E, Nagai, K.
Deposit date:2019-03-07
Release date:2019-04-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
5Z56
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BU of 5z56 by Molmil
cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z57
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BU of 5z57 by Molmil
Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
6HCF
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BU of 6hcf by Molmil
Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-14
Release date:2018-10-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6Y53
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BU of 6y53 by Molmil
human 17S U2 snRNP low resolution part
Descriptor: HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ...
Authors:Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H.
Deposit date:2020-02-24
Release date:2020-06-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
7DVQ
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BU of 7dvq by Molmil
Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ...
Authors:Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y.
Deposit date:2021-01-14
Release date:2021-03-31
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structure of the activated human minor spliceosome.
Science, 371, 2021
6FF7
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BU of 6ff7 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2019-03-13
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
4UCI
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BU of 4uci by Molmil
X-ray structure and activities of an essential Mononegavirales L- protein domain
Descriptor: ADENOSINE, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-10-14
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
7EVO
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BU of 7evo by Molmil
The cryo-EM structure of the human 17S U2 snRNP
Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-05-21
Release date:2022-08-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
8G5M
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BU of 8g5m by Molmil
Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D.
Deposit date:2023-02-13
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structural basis for DNA proofreading.
Nat Commun, 14, 2023
4UCZ
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BU of 4ucz by Molmil
X-ray structure and activities of an essential Mononegavirales L- protein domain
Descriptor: GUANOSINE, GUANOSINE-5'-TRIPHOSPHATE, RNA-DIRECTED RNA POLYMERASE L, ...
Authors:Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
6Y5Q
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BU of 6y5q by Molmil
human 17S U2 snRNP
Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ...
Authors:Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H.
Deposit date:2020-02-25
Release date:2020-06-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
8Y7E
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BU of 8y7e by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part
Descriptor: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
Authors:Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
Deposit date:2024-02-04
Release date:2024-03-13
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.66 Å)
Cite:Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024

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PDB entries from 2024-08-07

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