6TBM

Structure of SAGA bound to TBP, including Spt8 and DUB

Summary for 6TBM

• Entry DOI: 10.2210/pdb6tbm/pdb
• Related: 6TB4
• EMDB information: 10438 10440 10441 10446
• Descriptor: TATA-box Binding Protein (TBP), Subunit (60 kDa) of TFIID and SAGA complexes, Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation, ... (19 entities in total)
• Functional Keywords: transcriptional co-activator, histone-acetylation, transcription
• Biological source: Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast); More
• Total number of polymer chains: 18
• Total formula weight: 1280340.27

Authors

Papai, G.,Frechard, A.,Kolesnikova, O.,Crucifix, C.,Schultz, P.,Ben-Shem, A. (deposition date: 2019-11-01, release date: 2020-02-12, Last modification date: 2021-06-30)

• Primary citation: Papai, G.,Frechard, A.,Kolesnikova, O.,Crucifix, C.,Schultz, P.,Ben-Shem, A.; Structure of SAGA and mechanism of TBP deposition on gene promoters.; Nature, 577:711-716, 2020; PubMed: 31969704; DOI: 10.1038/s41586-020-1944-2

Experimental method

ELECTRON MICROSCOPY (20 Å)