8H6L

Cryo-EM structure of human exon-defined spliceosome in the early B state.

This is a non-PDB format compatible entry.

Summary for 8H6L

• Entry DOI: 10.2210/pdb8h6l/pdb
• Related: 8H6E 8H6J 8H6K
• EMDB information: 34500 34505 34507 34508
• Descriptor: pre-mRNA, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, ... (49 entities in total)
• Functional Keywords: exon-defined spliceosome, post pre-b state, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 59
• Total formula weight: 2507928.23

Authors

Zhang, W.,Zhan, X.,Zhang, X.,Bai, R.,Lei, J.,Yan, C.,Shi, Y. (deposition date: 2022-10-18, release date: 2024-05-01, Last modification date: 2024-05-08)

• Primary citation: Zhang, W.,Zhang, X.,Zhan, X.,Bai, R.,Lei, J.,Yan, C.,Shi, Y.; Structural insights into human exon-defined spliceosome prior to activation.; Cell Res., 2024; PubMed: 38658629; DOI: 10.1038/s41422-024-00949-w

Experimental method

ELECTRON MICROSCOPY (2.6 Å)