8H6E

Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.

This is a non-PDB format compatible entry.

Summary for 8H6E

• Entry DOI: 10.2210/pdb8h6e/pdb
• EMDB information: 34500
• Descriptor: pre-mRNA, U5 snRNA, Pre-mRNA-processing-splicing factor 8, ... (51 entities in total)
• Functional Keywords: exon-defined spliceosome, late pre-b state, rna splicing, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 61
• Total formula weight: 2736775.67

Authors

Zhang, W.,Zhan, X.,Zhang, X.,Bai, R.,Lei, J.,Yan, C.,Shi, Y. (deposition date: 2022-10-17, release date: 2024-05-01, Last modification date: 2024-05-08)

• Primary citation: Zhang, W.,Zhang, X.,Zhan, X.,Bai, R.,Lei, J.,Yan, C.,Shi, Y.; Structural insights into human exon-defined spliceosome prior to activation.; Cell Res., 2024; PubMed: 38658629; DOI: 10.1038/s41422-024-00949-w

Experimental method

ELECTRON MICROSCOPY (3.2 Å)