2IOY
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4B55
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![BU of 4b55 by Molmil](/molmil-images/mine/4b55) | Crystal Structure of the Covalent Adduct Formed between Mycobacterium marinum Aryalamine N-acetyltransferase and Phenyl vinyl ketone a derivative of Piperidinols | Descriptor: | 3-hydroxy-1-phenylpropan-1-one, ARYLAMINE N-ACETYLTRANSFERASE NAT | Authors: | Abuhammad, A, Fullam, E, Lowe, E.D, Staunton, D, Kawamura, A, Westwood, I.M, Bhakta, S, Garner, A.C, Wilson, D.L, Seden, P.T, Davies, S.G, Russell, A.J, Garman, E.F, Sim, E. | Deposit date: | 2012-08-02 | Release date: | 2013-01-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Piperidinols that Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages. Plos One, 7, 2012
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4BAI
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![BU of 4bai by Molmil](/molmil-images/mine/4bai) | Mycobacterium tuberculosis Chorismate synthase before exposure to 266 nm UV laser | Descriptor: | ACETATE ION, CHORISMATE SYNTHASE | Authors: | Pereira, P.J.B, Royant, A, Panjikar, S, de Sanctis, D. | Deposit date: | 2012-09-14 | Release date: | 2013-04-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures. J. Struct. Biol., 181, 2013
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4AU0
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![BU of 4au0 by Molmil](/molmil-images/mine/4au0) | Hypocrea jecorina Cel6A D221A mutant soaked with 6-chloro-4- methylumbelliferyl-beta-cellobioside | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-7-hydroxy-4-methyl-2H-chromen-2-one, EXOGLUCANASE 2, ... | Authors: | Wu, M, Nerinckx, W, Piens, K, Ishida, T, Hansson, H, Stahlberg, J, Sandgren, M. | Deposit date: | 2012-05-11 | Release date: | 2013-01-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Rational Design, Synthesis, Evaluation and Enzyme-Substrate Structures of Improved Fluorogenic Substrates for Family 6 Glycoside Hydrolases. FEBS J., 280, 2013
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2JLT
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![BU of 2jlt by Molmil](/molmil-images/mine/2jlt) | Crystal structure of an RNA kissing complex | Descriptor: | R06, TAR | Authors: | DiPrimo, C, Fribourg, S. | Deposit date: | 2008-09-15 | Release date: | 2009-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Exploring Tar-RNA Aptamer Loop-Loop Interaction by X-Ray Crystallography, Uv Spectroscopy and Surface Plasmon Resonance. Nucleic Acids Res., 36, 2008
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4B0Z
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![BU of 4b0z by Molmil](/molmil-images/mine/4b0z) | Crystal structure of S. pombe Rpn12 | Descriptor: | 26S PROTEASOME REGULATORY SUBUNIT RPN12, GLYCEROL, MONOTHIOGLYCEROL, ... | Authors: | Boehringer, J, Riedinger, C, Paraskevopoulos, K, Johnson, E.O.D, Lowe, E.D, Khoudian, C, Smith, D, Noble, M.E.M, Gordon, C, Endicott, J.A. | Deposit date: | 2012-07-06 | Release date: | 2012-09-12 | Last modified: | 2012-11-07 | Method: | X-RAY DIFFRACTION (1.585 Å) | Cite: | Structural and Functional Characterisation of Rpn12 Identifies Residues Required for Rpn10 Proteasome Incorporation. Biochem.J., 448, 2012
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2OUM
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![BU of 2oum by Molmil](/molmil-images/mine/2oum) | The first domain of L1 from Thermus thermophilus | Descriptor: | 50S ribosomal protein L1 | Authors: | Kljashtorny, V, Tishchenko, S, Nevskaya, N, Nikonov, S, Davydova, N, Garber, M. | Deposit date: | 2007-02-12 | Release date: | 2008-02-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Domain I of ribosomal protein L1 is sufficient for specific RNA binding. Nucleic Acids Res., 35, 2007
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4C30
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![BU of 4c30 by Molmil](/molmil-images/mine/4c30) | Crystal structure of Deinococcus radiodurans UvrD in complex with DNA, form 2 | Descriptor: | DNA HELICASE II, DNA STRAND FOR25, DNA STRAND REV25, ... | Authors: | Stelter, M, Acajjaoui, S, McSweeney, S, Timmins, J. | Deposit date: | 2013-08-21 | Release date: | 2013-10-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and Mechanistic Insight Into DNA Unwinding by Deinococcus Radiodurans Uvrd. Plos One, 8, 2013
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2P8G
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2ORW
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![BU of 2orw by Molmil](/molmil-images/mine/2orw) | Thermotoga maritima thymidine kinase 1 like enzyme in complex with TP4A | Descriptor: | MAGNESIUM ION, P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, Thymidine kinase, ... | Authors: | Segura-Pena, D, Lutz, S, Monnerjahn, C, Konrad, M, Lavie, A. | Deposit date: | 2007-02-04 | Release date: | 2007-03-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Binding of ATP to TK1-like Enzymes Is Associated with a Conformational Change in the Quaternary Structure. J.Mol.Biol., 369, 2007
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4BTX
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![BU of 4btx by Molmil](/molmil-images/mine/4btx) | Crystal structure of human vascular adhesion protein-1 in complex with pyridazinone inhibitors | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-isopropylamino-2-phenyl-6-(1H-1,2,4-triazol-5-yl)-3(2H)-pyridazinone, CALCIUM ION, ... | Authors: | Bligt-Linden, E, Pihlavisto, M, Szatmari, I, Otwinowski, Z, Smith, D.J, Lazar, L, Fulop, F, Salminen, T.A. | Deposit date: | 2013-06-19 | Release date: | 2013-12-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Novel Pyridazinone Inhibitors for Vascular Adhesion Protein- 1 (Vap-1): Old Target - New Inhibition Mode. J.Med.Chem., 56, 2013
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2OTT
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![BU of 2ott by Molmil](/molmil-images/mine/2ott) | Crystal structure of CD5_DIII | Descriptor: | T-cell surface glycoprotein CD5 | Authors: | Rodamilans, B. | Deposit date: | 2007-02-09 | Release date: | 2007-03-13 | Last modified: | 2021-03-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain. J.Biol.Chem., 282, 2007
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2OU9
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![BU of 2ou9 by Molmil](/molmil-images/mine/2ou9) | Structure of Spin-labeled T4 Lysozyme Mutant T115R1/R119A | Descriptor: | Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | Deposit date: | 2007-02-09 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme. Protein Sci., 16, 2007
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4BM1
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![BU of 4bm1 by Molmil](/molmil-images/mine/4bm1) | CRYSTAL STRUCTURE OF MANGANESE PEROXIDASE 4 FROM PLEUROTUS OSTREATUS - CRYSTAL FORM I | Descriptor: | CALCIUM ION, CITRIC ACID, MANGANESE PEROXIDASE 4, ... | Authors: | Medrano, F.J, Romero, A. | Deposit date: | 2013-05-05 | Release date: | 2014-01-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.098 Å) | Cite: | Ligninolytic Peroxidase Genes in the Oyster Mushroom Genome: Heterologous Expression, Molecular Structure, Catalytic and Stability Properties, and Lignin-Degrading Ability. Biotechnol.Biofuels, 7, 2014
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4DPR
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![BU of 4dpr by Molmil](/molmil-images/mine/4dpr) | Structure of human Leukotriene A4 hydrolase in complex with inhibitor captopril | Descriptor: | ACETIC ACID, GLYCEROL, L-CAPTOPRIL, ... | Authors: | Stsiapanava, A, Haeggstrom, J.Z, Rinaldo-Matthis, A. | Deposit date: | 2012-02-14 | Release date: | 2013-02-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Capturing LTA4hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4synthesis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2P35
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![BU of 2p35 by Molmil](/molmil-images/mine/2p35) | Crystal structure of trans-aconitate methyltransferase from Agrobacterium tumefaciens | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, Trans-aconitate 2-methyltransferase | Authors: | Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-03-08 | Release date: | 2007-04-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of trans-aconitate methyltransferase from Agrobacterium tumefaciens To be Published
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4DW1
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4DW4
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![BU of 4dw4 by Molmil](/molmil-images/mine/4dw4) | Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-UMP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... | Authors: | Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. | Deposit date: | 2012-02-24 | Release date: | 2012-05-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
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4DWC
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![BU of 4dwc by Molmil](/molmil-images/mine/4dwc) | Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with Zn ions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. | Deposit date: | 2012-02-24 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
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2P7P
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![BU of 2p7p by Molmil](/molmil-images/mine/2p7p) | Crystal structure of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes complexed with MN(II) and sulfate ion | Descriptor: | Glyoxalase family protein, MANGANESE (II) ION, SULFATE ION | Authors: | Fillgrove, K.L, Pakhomova, S, Schaab, M, Newcomer, M.E, Armstrong, R.N. | Deposit date: | 2007-03-20 | Release date: | 2007-07-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure and Mechanism of the Genomically Encoded Fosfomycin Resistance Protein, FosX, from Listeria monocytogenes. Biochemistry, 46, 2007
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2G81
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![BU of 2g81 by Molmil](/molmil-images/mine/2g81) | Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with Beta-trypsin at 1.55 Angstrons Resolution | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Bowman-Birk type seed trypsin and chymotrypsin inhibitor, ... | Authors: | Freitas, S.M, Barbosa, J.A.R.G, Paulino, L.S, Teles, R.C.L, Esteves, G.F, Ventura, M.M. | Deposit date: | 2006-03-01 | Release date: | 2007-01-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of the Bowman-Birk Inhibitor from Vigna unguiculata Seeds in Complex with {beta}-Trypsin at 1.55 A Resolution and Its Structural Properties in Association with Proteinases Biophys.J., 92, 2007
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4DZ7
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4DI8
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![BU of 4di8 by Molmil](/molmil-images/mine/4di8) | CRYSTAL STRUCTURE OF THE D248A mutant of 2-PYRONE-4,6-DICARBOXYLIC ACID HYDROLASE FROM SPHINGOMONAS PAUCIMOBILIS complexed with substrate at pH 8.5 | Descriptor: | (1E,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylic acid, 2-oxo-2H-pyran-4,6-dicarboxylic acid, 2-pyrone-4,6-dicarbaxylate hydrolase, ... | Authors: | Malashkevich, V.N, Toro, R, Hobbs, M.E, Raushel, F.M, Almo, S.C. | Deposit date: | 2012-01-11 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structure and Catalytic Mechanism of LigI: Insight into the Amidohydrolase Enzymes of cog3618 and Lignin Degradation. Biochemistry, 51, 2012
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4E0O
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![BU of 4e0o by Molmil](/molmil-images/mine/4e0o) | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form III) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | Authors: | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2012-03-04 | Release date: | 2012-12-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates. Proc.Natl.Acad.Sci.USA, 109, 2012
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2GIR
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![BU of 2gir by Molmil](/molmil-images/mine/2gir) | Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-1 inhibitor | Descriptor: | 3-{ISOPROPYL[(TRANS-4-METHYLCYCLOHEXYL)CARBONYL]AMINO}-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA-directed RNA polymerase | Authors: | Harris, S.F. | Deposit date: | 2006-03-29 | Release date: | 2007-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus. J.Virol., 80, 2006
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