4DPR

Structure of human Leukotriene A4 hydrolase in complex with inhibitor captopril

Summary for 4DPR

Entry DOI	10.2210/pdb4dpr/pdb
Descriptor	Leukotriene A-4 hydrolase, ZINC ION, L-CAPTOPRIL, ... (7 entities in total)
Functional Keywords	leukotriene a4, metalloprotein, protease, zinc binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P09960
Total number of polymer chains	1
Total formula weight	70756.10
Authors	Stsiapanava, A.,Haeggstrom, J.Z.,Rinaldo-Matthis, A. (deposition date: 2012-02-14, release date: 2013-02-20, Last modification date: 2023-09-13)
Primary citation	Stsiapanava, A.,Samuelsson, B.,Haeggstrom, J.Z. Capturing LTA4hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4synthesis. Proc. Natl. Acad. Sci. U.S.A., 114:9689-9694, 2017 Cited by PubMed: 28827365 DOI: 10.1073/pnas.1710850114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.02 Å)

Structure validation