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4DW1

Crystal structure of the ATP-gated P2X4 ion channel in the ATP-bound, open state at 2.8 Angstroms

Summary for 4DW1
Entry DOI10.2210/pdb4dw1/pdb
Related4DW0
DescriptorP2X purinoceptor, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordsion channel, transport protein
Biological sourceDanio rerio (leopard danio,zebra danio,zebra fish)
Cellular locationMembrane; Multi-pass membrane protein (By similarity): Q6NYR1
Total number of polymer chains1
Total formula weight40103.17
Authors
Hattori, M.,Gouaux, E. (deposition date: 2012-02-24, release date: 2012-04-25, Last modification date: 2020-07-29)
Primary citationHattori, M.,Gouaux, E.
Molecular mechanism of ATP binding and ion channel activation in P2X receptors.
Nature, 485:207-212, 2012
Cited by
PubMed: 22535247
DOI: 10.1038/nature11010
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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