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PDB: 259 results
3DDK
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BU of 3ddk by Molmil
Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase
Descriptor: RNA polymerase B3 3Dpol, SODIUM ION, SULFATE ION
Authors:Campagnola, G, Weygandt, M.H, Scoggin, K.E, Peersen, O.B.
Deposit date:2008-06-05
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Coxsackievirus B3 3Dpol Highlights Functional Importance of Residue 5 in Picornaviral Polymerases
J.Virol., 82, 2008
5Y6Z
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BU of 5y6z by Molmil
Crystal structure of the coxsackievirus A16 polymerase elongation complex
Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
Authors:Bi, P, Shu, B, Gong, P.
Deposit date:2017-08-15
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics
Virol Sin, 32, 2017
5XE0
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BU of 5xe0 by Molmil
Crystal structure of EV-D68-3Dpol in complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein
Authors:Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C.
Deposit date:2017-03-30
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol
J. Virol., 91, 2017
5JXS
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BU of 5jxs by Molmil
Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: MAGNESIUM ION, RNA Primer, RNA Template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-05-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
5TSN
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BU of 5tsn by Molmil
Crystal structures of Norwalk virus polymerase bound to an RNA primer-template duplex
Descriptor: MANGANESE (II) ION, Norwalk virus polymerase, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3')
Authors:Shaik, M.M, Ng, K.K.
Deposit date:2016-10-30
Release date:2017-04-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences.
Proteins, 85, 2017
1WAC
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BU of 1wac by Molmil
Back-priming mode of Phi6 RNA-dependent RNA polymerase
Descriptor: P2 PROTEIN
Authors:Laurila, M.R.L, Salgado, P.S, Stuart, D.I, Grimes, J.M, Bamford, D.H.
Deposit date:2004-10-26
Release date:2005-01-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Back-Priming Mode of Phi6 RNA-Dependent RNA Polymerase
J.Gen.Virol., 86, 2005
5N8X
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BU of 5n8x by Molmil
Trigonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: 3D polymerase, GLYCEROL, MANGANESE (II) ION
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2017-02-24
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.
Genome Biol Evol, 9, 2017
5N95
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BU of 5n95 by Molmil
Tetragonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: 3D polymerase, TRIPHOSPHATE
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2017-02-24
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.
Genome Biol Evol, 9, 2017
1WNE
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BU of 1wne by Molmil
Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA
Descriptor: 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2004-07-31
Release date:2004-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA
J.Biol.Chem., 279, 2004
8TUF
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BU of 8tuf by Molmil
Crystal structure of human norovirus RNA-dependent RNA-polymerase
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, RNA-dependent RNA-polymerase
Authors:Prasad, B.V.V, Kaundal, S, Sankaran, B.
Deposit date:2023-08-16
Release date:2024-12-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of human norovirus RNA-dependent RNA-polymerase
To Be Published
3CDU
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BU of 3cdu by Molmil
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3CDW
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BU of 3cdw by Molmil
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3H5X
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BU of 3h5x by Molmil
Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase
Descriptor: 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate), 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ...
Authors:Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S.
Deposit date:2009-04-22
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
8IIC
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BU of 8iic by Molmil
Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta40 mutant (residues 41-546)
Descriptor: Polymerase polyprotein
Authors:Fang, X, Lu, G, Hou, C, Gong, P.
Deposit date:2023-02-24
Release date:2023-06-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
8IIB
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BU of 8iib by Molmil
Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546)
Descriptor: CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Fang, X, Lu, G, Hou, C, Gong, P.
Deposit date:2023-02-24
Release date:2023-06-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
5I61
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BU of 5i61 by Molmil
Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus
Descriptor: Potential RNA-dependent RNA polymerase
Authors:Collier, A.M, Guo, Y.R, Tao, Y.J.
Deposit date:2016-02-15
Release date:2016-03-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
6GVV
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BU of 6gvv by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus
Descriptor: GLYCEROL, RNA polymerase 3D
Authors:Verdaguer, N, Ferrer Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J.Virol., 92, 2018
5I62
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BU of 5i62 by Molmil
Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus
Descriptor: Potential RNA-dependent RNA polymerase
Authors:Collier, A.M, Guo, Y.R, Tao, Y.J.
Deposit date:2016-02-15
Release date:2016-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
6GVY
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BU of 6gvy by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA
Descriptor: GLYCEROL, Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J. Virol., 92, 2018
8C2P
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BU of 8c2p by Molmil
FMDV 3D polymerase in complex with 3B3
Descriptor: Protein 3B-3, RNA-directed RNA polymerase 3D-POL
Authors:Ferrer-Orta, C, Veraguer, N.
Deposit date:2022-12-22
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
Plos Pathog., 19, 2023
8C1N
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BU of 8c1n by Molmil
FMDV 3D polymerase in complex with 3B1 protein solved in P212121 space group
Descriptor: ACETATE ION, GLYCEROL, Protein 3B-1, ...
Authors:Ferrer-Orta, C, Veraguer, N.
Deposit date:2022-12-20
Release date:2023-04-26
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
Plos Pathog., 19, 2023
3H5Y
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BU of 3h5y by Molmil
Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2
Descriptor: 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S.
Deposit date:2009-04-22
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
3BSN
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BU of 3bsn by Molmil
Norwalk Virus polymerase bound to 5-nitrocytidine triphosphate and primer-template RNA
Descriptor: 5-nitrocytidine 5'-(tetrahydrogen triphosphate), GLYCEROL, MANGANESE (II) ION, ...
Authors:Zamyatkin, D.F, Ng, K.K.S.
Deposit date:2007-12-26
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.
J.Biol.Chem., 283, 2008
3BSO
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BU of 3bso by Molmil
Norwalk Virus polymerase bound to cytidine 5'-triphosphate and primer-template RNA
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
Authors:Zamyatkin, D.F, Ng, K.K.S.
Deposit date:2007-12-26
Release date:2008-01-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.
J.Biol.Chem., 283, 2008
4IKA
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BU of 4ika by Molmil
Crystal structure of EV71 3Dpol-VPg
Descriptor: 3Dpol, NICKEL (II) ION, VPg
Authors:Chen, C, Wang, Y.X, Lou, Z.Y.
Deposit date:2012-12-25
Release date:2013-09-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: implication for a trans mechanism of VPg uridylylation
J.Virol., 87, 2013

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