3CDW
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate
Summary for 3CDW
Entry DOI | 10.2210/pdb3cdw/pdb |
Related | 1XR5 2E9Z 2F8E 2ILZ 3CDU |
Descriptor | RNA-directed RNA polymerase 3D-POL, Protein 3B, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | coxsackievirus, rna-dependent rna polymerase, protein primer, vpg, vizier viral enzymes involved in replication, transferase-viral protein complex, transferase/viral protein |
Biological source | Coxsackievirus B3 More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03313 P03313 |
Total number of polymer chains | 2 |
Total formula weight | 58955.59 |
Authors | Gruez, A.,Selisko, B.,Roberts, M.,Bricogne, G.,Bussetta, C.,Canard, B. (deposition date: 2008-02-27, release date: 2008-07-22, Last modification date: 2023-11-01) |
Primary citation | Gruez, A.,Selisko, B.,Roberts, M.,Bricogne, G.,Bussetta, C.,Jabafi, I.,Coutard, B.,De Palma, A.M.,Neyts, J.,Canard, B. The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82:9577-9590, 2008 Cited by PubMed: 18632861DOI: 10.1128/JVI.00631-08 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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