5N95
Tetragonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus
Summary for 5N95
| Entry DOI | 10.2210/pdb5n95/pdb |
| Descriptor | 3D polymerase, TRIPHOSPHATE (3 entities in total) |
| Functional Keywords | 3dpolymerase, rna dependent rna polymerases, 5'-fluoracil, nucleotide analogues, viral protein |
| Biological source | Foot-and-mouth disease virus |
| Cellular location | Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Virion : A4H1Z0 |
| Total number of polymer chains | 1 |
| Total formula weight | 54382.32 |
| Authors | Ferrer-Orta, C.,Verdaguer, N. (deposition date: 2017-02-24, release date: 2017-05-10, Last modification date: 2024-01-17) |
| Primary citation | de la Higuera, I.,Ferrer-Orta, C.,de Avila, A.I.,Perales, C.,Sierra, M.,Singh, K.,Sarafianos, S.G.,Dehouck, Y.,Bastolla, U.,Verdaguer, N.,Domingo, E. Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus. Genome Biol Evol, 9:1212-1228, 2017 Cited by PubMed: 28460010DOI: 10.1093/gbe/evx075 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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