6GVY

Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA

Summary for 6GVY

• Entry DOI: 10.2210/pdb6gvy/pdb
• Descriptor: Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), RNA (5'-R(P*CP*UP*CP*CP*CP*GP*GP*G)-3'), ... (5 entities in total)
• Functional Keywords: rna dependent rna polymerase, picornavirus, closed right hand conformation, viral protein
• Biological source: Foot-and-mouth disease virus - type C; More
• Total number of polymer chains: 3
• Total formula weight: 58260.89

Authors

Verdaguer, N.,Ferrer-Orta, C. (deposition date: 2018-06-21, release date: 2018-08-01, Last modification date: 2024-01-17)

• Primary citation: de la Higuera, I.,Ferrer-Orta, C.,Moreno, E.,de Avila, A.I.,Soria, M.E.,Singh, K.,Caridi, F.,Sobrino, F.,Sarafianos, S.G.,Perales, C.,Verdaguer, N.,Domingo, E.; Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.; J. Virol., 92:-, 2018; PubMed: 30068642; DOI: 10.1128/JVI.01119-18

Experimental method

X-RAY DIFFRACTION (2.2 Å)