6GVY

Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Genome polyprotein	polymer	481	54050.2	1	UniProt (Q0QEE0) Pfam (PF00680) UniProt (by SIFTS) (P03311)	Foot-and-mouth disease virus - type C
2	B (B)	RNA (5'-R(P*CP*CP*GP*GP*G)-3')	polymer	5	1601.0	1		synthetic construct
3	C (C)	RNA (5'-R(P*CP*UP*CP*CP*CP*GP*GP*G)-3')	polymer	8	2517.6	1		synthetic construct
4	D (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	E, F, G (A, B, C)	water	water		18.0	42	Chemie (HOH)

Sequence modifications

A: 1 - 470 (UniProt: Q0QEE0)

PDB	External Database	Details
Ala 16	Met 1540	engineered mutation
Ala 471	-	expression tag
Ala 472	-	expression tag
Ala 473	-	expression tag
Leu 474	-	expression tag
Glu 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	58168.8
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	58260.9

*Water molecules are not included.