3H5X
Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase
Summary for 3H5X
Entry DOI | 10.2210/pdb3h5x/pdb |
Related | 1SH0 3BSN 3BSO 3H5Y |
Descriptor | RNA dependent RNA polymerase, 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ... (7 entities in total) |
Functional Keywords | polymerase-rna complex, non-natural nucleoside triphosphate analog, calicivirus, hydrolase, nucleotide-binding, nucleotidyltransferase, protease, rna replication, rna-directed rna polymerase, thiol protease, transferase, transferase-rna complex, transferase/rna |
Biological source | Norwalk virus |
Total number of polymer chains | 3 |
Total formula weight | 63334.21 |
Authors | Zamyatkin, D.F.,Parra, F.,Machin, A.,Grochulski, P.,Ng, K.K.S. (deposition date: 2009-04-22, release date: 2009-05-19, Last modification date: 2023-09-06) |
Primary citation | Zamyatkin, D.F.,Parra, F.,Machin, A.,Grochulski, P.,Ng, K.K. Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390:10-16, 2009 Cited by PubMed: 19426741DOI: 10.1016/j.jmb.2009.04.069 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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