3H5X
Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | RNA dependent RNA polymerase | polymer | 510 | 56843.6 | 1 | UniProt (Q70ET3) Pfam (PF00680) In PDB | Norwalk virus | |
| 2 | P | 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3' | polymer | 8 | 2557.6 | 1 | |||
| 3 | T | 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3' | polymer | 9 | 2862.8 | 1 | |||
| 4 | A | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 5 | A | 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate) | non-polymer | 482.2 | 1 | Chemie (CSG) | |||
| 6 | A, T | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 441 | Chemie (HOH) |
Sequence modifications
A: 1 - 510 (UniProt: Q70ET3)
| PDB | External Database | Details |
|---|---|---|
| Ser 2 | Gly 330 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62263.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1070.3 | |
| All* | Total formula weight | 63334.2 |
